| Gene Symbol |
P2RY13
|
| Entrez Gene |
53829
|
| Alt Symbol |
FKSG77, GPCR1, GPR86, GPR94, P2Y13, SP174
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
purinergic receptor P2Y, G-protein coupled, 13
|
| Other Description |
G protein-coupled receptor 86|G-protein coupled receptor 86|G-protein coupled receptor 94|P2Y purinoceptor 13
|
| Swissprots |
Q8IUT5 Q6DKN4 Q8TDU7 Q05C50 Q9BY61 B2R827 Q9BPV8
|
| Accessions |
AAL26484 BAB89310 CAJ33696 EAW78805 EAW78806 EAW78807 Q9BPV8 AF178982 AAK18752 AF295368 AAK01864 AF345565 AAK29068 AF406692 AAL01038 AK313208 BAG36024 BC029363 AAH29363 BC041116 AAH41116 BC066887 AAH66887 DA676457 JF810883 AEP43750 XM_006713664 XP_006713727 NM_176894 NP_795713 NM_023914
|
| Function |
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. {ECO:0000269|PubMed:11546776}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|
![Western Blot: GPR86 Overexpression Lysate (Adult Normal) [NBL1-14041] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GPR86.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7836_GPR86%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14041-img0002.jpg)