Gene Symbol | P2RY13 |
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Entrez Gene | 53829 |
Alt Symbol | FKSG77, GPCR1, GPR86, GPR94, P2Y13, SP174 |
Species | Human |
Gene Type | protein-coding |
Description | purinergic receptor P2Y, G-protein coupled, 13 |
Other Description | G protein-coupled receptor 86|G-protein coupled receptor 86|G-protein coupled receptor 94|P2Y purinoceptor 13 |
Swissprots | Q8IUT5 Q6DKN4 Q8TDU7 Q05C50 Q9BY61 B2R827 Q9BPV8 |
Accessions | AAL26484 BAB89310 CAJ33696 EAW78805 EAW78806 EAW78807 Q9BPV8 AF178982 AAK18752 AF295368 AAK01864 AF345565 AAK29068 AF406692 AAL01038 AK313208 BAG36024 BC029363 AAH29363 BC041116 AAH41116 BC066887 AAH66887 DA676457 JF810883 AEP43750 XM_006713664 XP_006713727 NM_176894 NP_795713 NM_023914 |
Function | Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. {ECO:0000269|PubMed:11546776}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human GPCR GPR86 full length protein - ab162700 from Abcam
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P2Y13 / P2RY13 Antibody Blocking Peptide - LS-E23661 from LifeSpan Bioscience
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P2Y13 / P2RY13 Antibody Blocking Peptide - LS-E23662 from LifeSpan Bioscience
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P2Y13 / P2RY13 Antibody Blocking Peptide - LS-E28999 from LifeSpan Bioscience
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P2Y13 / P2RY13 Antibody Blocking Peptide - LS-E29008 from LifeSpan Bioscience
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P2Y13 / P2RY13 Antibody Blocking Peptide - LS-E28355 from LifeSpan Bioscience
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P2Y13 / P2RY13 Antibody Blocking Peptide - LS-E28357 from LifeSpan Bioscience
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P2Y13 / P2RY13 Antibody Blocking Peptide - LS-E28358 from LifeSpan Bioscience
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Recombinant Human P2Y13/P2RY13/GPR86 Protein - H00053829-P01 from Novus Biologicals
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P2RY13-Antibody-Center-Blocking-Peptide - BP17023c from Abgent, a WuXi AppTec company
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P2Y13 / P2YR13 - H00053829-P01 from Acris Antibodies
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P2Y13 / P2YR13 Control Peptide - AP05305CP-N from Acris Antibodies
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P2Y13 / P2YR13 Control Peptide - SP4265CP from Acris Antibodies
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P2RY13 fusion protein - Ag14779 from Proteintech Group
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P2RY13 fusion protein - Ag14108 from Proteintech Group
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P2RY13 Peptide (OEEG01161) - OEEG01161 from Aviva Systems Biology
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G-Protein Coupled Receptor 94, Peptide - MBS396452 from MyBioSource
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P2Y13/P2RY13/GPR86 Recombinant Protein Antigen - NBP2-13721PEP from Novus Biologicals
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GPR86 Blocking Peptide - abx161973 from Abbexa
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P2RY13 Peptide, Human - M34GP11208H from Creative Peptides
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GPR86 Blocking Peptide - CBP4762 from Cohesion Biosciences
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P2Y purinoceptor 13 (P2RY13), Recombinant Protein - MBS7025277 from MyBioSource
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GPR86 peptide - orb315906 from Biorbyt
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