Gene Symbol | RFX4 |
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Entrez Gene | 5992 |
Alt Symbol | NYD-SP10 |
Species | Human |
Gene Type | protein-coding |
Description | regulatory factor X, 4 (influences HLA class II expression) |
Other Description | testis development protein NYD-SP10|transcription factor RFX4|winged-helix transcription factor RFX4 |
Swissprots | Q8NC78 Q8NDF9 B2RDW4 Q33DW6 Q8SNA1 Q33E95 Q33E94 Q9BXI0 Q8MHQ1 Q33DW7 A8K5Y0 Q6YM53 Q96S80 |
Accessions | EAW97782 EAW97783 EAW97784 Q33E94 AB044245 BAB59001 AB095365 BAE48231 AB095366 BAE48232 AB195784 BAE48237 AB195785 BAE48238 AF332192 AAK17191 AI002078 AI191585 AK074913 BAC11288 AK291445 BAF84134 AK302837 BAG64029 AK315698 BAG38061 AL833921 CAD38777 AY102009 AAM52484 BC028582 AAH28582 BC030644 AAH30644 DB445991 DQ890831 ABM81757 DQ893986 ABM84912 NM_001206691 NP_001193620 NM_032491 NP_115880 NM_213594 NP_998759 NM_002920 |
Function | May activate transcription by interacting directly with the X-box. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00858}. |
Tissue Specificity | Isoform 4 is testis-specific. Isoform 1 is expressed in brain and gliomas. Isoform 2 and isoform 3 are testis-specific (at protein level). Isoform 1 is expressed in brain (at protein level). Isoform 3 is expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes. {ECO:0000269|PubMed:11682486, ECO:0000269|PubMed:16193984, ECO:0000269|PubMed:16271074}. |
RFX4 (E-14) - sc-132790 from Santa Cruz Biotechnology
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RFX4 (F-15) - sc-132791 from Santa Cruz Biotechnology
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RFX4 (S-25) - sc-102081 from Santa Cruz Biotechnology
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Anti-RFX4 antibody - ab168498 from Abcam
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Anti-RFX4 antibody - ab188020 from Abcam
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Anti-RFX4 antibody - ab179595 from Abcam
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Anti-RFX4 antibody - ab50673 from Abcam
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Anti-RFX4 antibody - ab189834 from Abcam
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Anti-RFX4 antibody - C-terminal - ab199881 from Abcam
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Anti-RFX4 Antibody (aa22-71) - LS-C30291 from LifeSpan Bioscience
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Anti-RFX4 Antibody (aa352-401) - LS-C31698 from LifeSpan Bioscience
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Anti-RFX4 Antibody (aa154-203) - LS-C201271 from LifeSpan Bioscience
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Anti-RFX4 Antibody (aa109-158) - LS-C80282 from LifeSpan Bioscience
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Anti-RFX4 Antibody (aa144-193) - LS-C109967 from LifeSpan Bioscience
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Anti-RFX4 Antibody (aa58-89) - LS-C344575 from LifeSpan Bioscience
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RFX4 Antibody - NBP2-15099 from Novus Biologicals
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RFX4 Antibody - H00005992-B01P from Novus Biologicals
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RFX4 Polyclonal Antibody - bs-11943R from Bioss
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RFX4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11943R-A350 from Bioss
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RFX4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11943R-A488 from Bioss
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RFX4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11943R-A555 from Bioss
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RFX4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11943R-A647 from Bioss
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RFX4 Polyclonal Antibody, Cy3 Conjugated - bs-11943R-Cy3 from Bioss
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RFX4 Polyclonal Antibody, Cy5 Conjugated - bs-11943R-Cy5 from Bioss
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RFX4 Polyclonal Antibody, Cy5.5 Conjugated - bs-11943R-Cy5.5 from Bioss
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