Gene Symbol | RFX4 |
---|---|
Entrez Gene | 5992 |
Alt Symbol | NYD-SP10 |
Species | Human |
Gene Type | protein-coding |
Description | regulatory factor X, 4 (influences HLA class II expression) |
Other Description | testis development protein NYD-SP10|transcription factor RFX4|winged-helix transcription factor RFX4 |
Swissprots | Q8NC78 Q8NDF9 B2RDW4 Q33DW6 Q8SNA1 Q33E95 Q33E94 Q9BXI0 Q8MHQ1 Q33DW7 A8K5Y0 Q6YM53 Q96S80 |
Accessions | EAW97782 EAW97783 EAW97784 Q33E94 AB044245 BAB59001 AB095365 BAE48231 AB095366 BAE48232 AB195784 BAE48237 AB195785 BAE48238 AF332192 AAK17191 AI002078 AI191585 AK074913 BAC11288 AK291445 BAF84134 AK302837 BAG64029 AK315698 BAG38061 AL833921 CAD38777 AY102009 AAM52484 BC028582 AAH28582 BC030644 AAH30644 DB445991 DQ890831 ABM81757 DQ893986 ABM84912 NM_001206691 NP_001193620 NM_032491 NP_115880 NM_213594 NP_998759 NM_002920 |
Function | May activate transcription by interacting directly with the X-box. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00858}. |
Tissue Specificity | Isoform 4 is testis-specific. Isoform 1 is expressed in brain and gliomas. Isoform 2 and isoform 3 are testis-specific (at protein level). Isoform 1 is expressed in brain (at protein level). Isoform 3 is expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes. {ECO:0000269|PubMed:11682486, ECO:0000269|PubMed:16193984, ECO:0000269|PubMed:16271074}. |
RFX4 CRISPR/Cas9 KO Plasmid (h) - sc-406366 from Santa Cruz Biotechnology
|
||||||||
RFX4 HDR Plasmid (h) - sc-406366-HDR from Santa Cruz Biotechnology
|
||||||||
RFX4 Double Nickase Plasmid (h) - sc-406366-NIC from Santa Cruz Biotechnology
|
||||||||
RFX4 Double Nickase Plasmid (h2) - sc-406366-NIC-2 from Santa Cruz Biotechnology
|
||||||||
RFX4 CRISPR Activation Plasmid (h) - sc-406366-ACT from Santa Cruz Biotechnology
|
||||||||
RFX4 CRISPR Activation Plasmid (h2) - sc-406366-ACT-2 from Santa Cruz Biotechnology
|
||||||||
RFX4 Lentiviral Activation Particles (h) - sc-406366-LAC from Santa Cruz Biotechnology
|
||||||||
RFX4 Lentiviral Activation Particles (h2) - sc-406366-LAC-2 from Santa Cruz Biotechnology
|
||||||||
RFX4 siRNA (h) - sc-95773 from Santa Cruz Biotechnology
|
||||||||
RFX4 shRNA Plasmid (h) - sc-95773-SH from Santa Cruz Biotechnology
|
||||||||
RFX4 shRNA (h) Lentiviral Particles - sc-95773-V from Santa Cruz Biotechnology
|
||||||||
RFX4 RNAi - H00005992-R02 from Novus Biologicals
|
||||||||
RFX4 RNAi - H00005992-R03 from Novus Biologicals
|
||||||||
RFX4 RNAi - H00005992-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU059161 from Sigma-Aldrich
|
||||||||
MISSION® esiRNA - EHU029681 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN18187 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18187 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR09038 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR03719 from Sigma-Aldrich
|
||||||||
RFX4 siRNA (Human) - CRH4060 from Cohesion Biosciences
|
||||||||
RFX4 - MBS8213776 from MyBioSource
|
||||||||
RFX4 HDR Plasmid (h2) - sc-406366-HDR-2 from Santa Cruz Biotechnology
|
||||||||
RFX4 CRISPR/Cas9 KO Plasmid (h2) - sc-406366-KO-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human RFX4 (NM_032491.5) - SHH392424 from Creative biogene
|