| Gene Symbol |
AKR1E2
|
| Entrez Gene |
83592
|
| Alt Symbol |
AKR1CL2, AKRDC1, LoopADR, hTSP, htAKR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
aldo-keto reductase family 1, member E2
|
| Other Description |
1,5-anhydro-D-fructose reductase|AF reductase|aldo-keto reductase family 1 member C-like protein 2|aldo-keto reductase family 1, member C-like 2|aldo-keto reductase loopADR|testis-specific protein
|
| Swissprots |
Q96JD6 Q9BU71 Q86Z16 Q86Z18 Q86Z17
|
| Accessions |
EAW86461 EAW86462 EAW86463 EAW86464 EAW86465 EAW86466 Q96JD6 AB040820 BAC54565 AB040821 BAC54566 AB040822 BAC54567 AB055603 BAC54568 AF263242 AAK58523 AK074211 AK302155 BAH13638 BC002862 AAH02862 BC023972 BI756016 BM724648 BU741321 DA006578 HQ447817 ADQ32301 XM_006717514 XP_006717577 XM_011519715 XP_011518017 XM_011519716 XP_011518018 XM_011519717 XP_011518019 XM_011519718 XP_011518020 XM_011519719 XP_011518021 XM_011519720 XP_011518022 XM_011519721 XP_011518023 XM_011519722 XP_011518024 XM_011519723 XP_011518025 XM_011519724 XP_011518026 XM_011519725 XP_011518027 XM_011519726 XP_011518028 XM_011519727 XP_011518029 XM_011519728 XP_011518030 XM_011519729 XP_011518031 XR_930518 XR_930519 XR_930520 NM_001040177 NP_001035267 NM_001271021 NP_001257950 NM_001271025 NP_001257954 NR_073125 NR_073126 NR_073127 NM_031436
|
| Function |
Catalyzes the NADPH-dependent reduction of 1,5-anhydro- D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones (By similarity). Has low NADPH-dependent reductase activity towards 9,10- phenanthrenequinone (in vitro). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}.
|
| Tissue Specificity |
Testis-specific. {ECO:0000269|PubMed:12604216}.
|
![Western Blot: AKR1CL2 Overexpression Lysate [H00083592-T01] - Lane 1: AKR1CL2 transfected lysate (33.88 KDa) Lane 2: Non-transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26566_AKR1CL2%2520Overexpression%2520Lysate-Western%2520Blot-H00083592-T01-img0002.jpg)
![Western Blot: AKR1CL2 Overexpression Lysate (Adult Normal) [NBP2-10632] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AKR1CL2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6839_AKR1CL2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10632-img0001.jpg)