| Gene Symbol | AKR1E2 |
|---|---|
| Entrez Gene | 83592 |
| Alt Symbol | AKR1CL2, AKRDC1, LoopADR, hTSP, htAKR |
| Species | Human |
| Gene Type | protein-coding |
| Description | aldo-keto reductase family 1, member E2 |
| Other Description | 1,5-anhydro-D-fructose reductase|AF reductase|aldo-keto reductase family 1 member C-like protein 2|aldo-keto reductase family 1, member C-like 2|aldo-keto reductase loopADR|testis-specific protein |
| Swissprots | Q96JD6 Q9BU71 Q86Z16 Q86Z18 Q86Z17 |
| Accessions | EAW86461 EAW86462 EAW86463 EAW86464 EAW86465 EAW86466 Q96JD6 AB040820 BAC54565 AB040821 BAC54566 AB040822 BAC54567 AB055603 BAC54568 AF263242 AAK58523 AK074211 AK302155 BAH13638 BC002862 AAH02862 BC023972 BI756016 BM724648 BU741321 DA006578 HQ447817 ADQ32301 XM_006717514 XP_006717577 XM_011519715 XP_011518017 XM_011519716 XP_011518018 XM_011519717 XP_011518019 XM_011519718 XP_011518020 XM_011519719 XP_011518021 XM_011519720 XP_011518022 XM_011519721 XP_011518023 XM_011519722 XP_011518024 XM_011519723 XP_011518025 XM_011519724 XP_011518026 XM_011519725 XP_011518027 XM_011519726 XP_011518028 XM_011519727 XP_011518029 XM_011519728 XP_011518030 XM_011519729 XP_011518031 XR_930518 XR_930519 XR_930520 NM_001040177 NP_001035267 NM_001271021 NP_001257950 NM_001271025 NP_001257954 NR_073125 NR_073126 NR_073127 NM_031436 |
| Function | Catalyzes the NADPH-dependent reduction of 1,5-anhydro- D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones (By similarity). Has low NADPH-dependent reductase activity towards 9,10- phenanthrenequinone (in vitro). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000305}. |
| Tissue Specificity | Testis-specific. {ECO:0000269|PubMed:12604216}. |