Gene Symbol | TRPC1 |
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Entrez Gene | 7220 |
Alt Symbol | HTRP-1, TRP1 |
Species | Human |
Gene Type | protein-coding |
Description | transient receptor potential cation channel, subfamily C, member 1 |
Other Description | TRP-1|capacitative calcium channel protein Trp1|short transient receptor potential channel 1|transient receptor potential canonical 1|transient receptor protein 1 |
Swissprots | Q14CE4 P48995 |
Accessions | CAJ01296 EAW78963 EAW78964 P48995 AB255425 BAF76425 AF483645 AAM97860 AI280444 BC112338 AAI12339 BC113953 AAI13954 BX331349 DB185459 EF522961 ABP94017 GQ293239 ACT66710 X89066 CAA61447 XM_005247738 XP_005247795 XM_005247739 XP_005247796 XR_241506 XR_924164 XR_924165 XR_924166 NM_001251845 NP_001238774 NM_003304 NP_003295 |
Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. {ECO:0000269|PubMed:15016832}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Seems to be ubiquitous. |
Top Pathways | Pancreatic secretion, Glutamatergic synapse |
TRPC1 (E-6) - sc-133076 from Santa Cruz Biotechnology
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TRPC1 (C-14) - sc-15055 from Santa Cruz Biotechnology
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TRPC1 (H-105) - sc-20110 from Santa Cruz Biotechnology
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TRPC1 (A-14) - sc-23011 from Santa Cruz Biotechnology
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Anti-TRPC1 [EPR1417(2)] antibody - ab192031 from Abcam
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Anti-TRPC1 antibody - ab74819 from Abcam
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Anti-TRPC1 antibody - ab75322 from Abcam
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Anti-TRPC1 antibody - ab63074 from Abcam
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Anti-TRPC1 antibody - ab84160 from Abcam
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Anti-TRPC1 antibody - ab110837 from Abcam
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Anti-TRPC1 antibody [EP1417Y] - ab51255 from Abcam
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Anti-TRPC1 Antibody (aa700-750) - LS-C94998 from LifeSpan Bioscience
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Anti-TRPC1 Antibody - LS-C95218 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (2nd Extracellular Domain) - LS-C136510 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (C-Terminus) - LS-C153552 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (C-Terminus) - LS-C144822 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (aa765-793, APC) - LS-C272295 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (aa765-793, AP) - LS-C272294 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (aa765-793, Biotin) - LS-C272296 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (aa765-793, FITC) - LS-C272297 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (aa765-793, Azide-free, HRP) - LS-C272298 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (aa765-793, PE) - LS-C272300 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (aa764-793) - LS-C325981 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (aa765-793) - LS-C160227 from LifeSpan Bioscience
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Anti-TRPC1 Antibody (clone 1E4) - LS-C198370 from LifeSpan Bioscience
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