| Gene Symbol |
ARSG
|
| Entrez Gene |
22901
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
arylsulfatase G
|
| Other Description |
ASG
|
| Swissprots |
Q6UXF2 Q9Y2K4 Q96EG1
|
| Accessions |
CAC60188 EAW89055 EAW89056 Q96EG1 AB023218 BAA76845 AK311327 AY358380 AAQ88746 BC012375 AAH12375 BG700864 XM_005257170 XP_005257227 XM_005257172 XP_005257229 XM_006721777 XP_006721840 XM_006721779 XP_006721842 XM_011524535 XP_011522837 XM_011524536 XP_011522838 XM_011524537 XP_011522839 XM_011524538 XP_011522840 XM_011524539 XP_011522841 XM_011524540 XP_011522842 XM_011524541 XP_011522843 XM_011524542 XP_011522844 XM_011524543 XP_011522845 XM_011524544 XP_011522846 XM_011524545 XP_011522847 XM_011524546 XP_011522848 XR_934425 NM_001267727 NP_001254656 NM_014960 NP_055775
|
| Function |
Displays arylsulfatase activity at acidic pH with pseudosubstrates, such as p-nitrocatechol sulfate and also, but with lower activity, p-nitrophenyl sulfate and 4- methylumbelliferyl sulfate. {ECO:0000269|PubMed:18283100}.
|
| Subcellular Location |
Lysosome {ECO:0000269|PubMed:12461688, ECO:0000269|PubMed:18283100}. Note=Previously observed endoplasmic reticulum localization is most likely due to folding/maturation problems for overexpressed proteins.
|
| Tissue Specificity |
Widely expressed, with very low expression in brain, lung, heart and skeletal muscle. {ECO:0000269|PubMed:12461688, ECO:0000269|PubMed:18283100}.
|
| Top Pathways |
Lysosome
|