Gene Symbol | ARSG |
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Entrez Gene | 22901 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | arylsulfatase G |
Other Description | ASG |
Swissprots | Q6UXF2 Q9Y2K4 Q96EG1 |
Accessions | CAC60188 EAW89055 EAW89056 Q96EG1 AB023218 BAA76845 AK311327 AY358380 AAQ88746 BC012375 AAH12375 BG700864 XM_005257170 XP_005257227 XM_005257172 XP_005257229 XM_006721777 XP_006721840 XM_006721779 XP_006721842 XM_011524535 XP_011522837 XM_011524536 XP_011522838 XM_011524537 XP_011522839 XM_011524538 XP_011522840 XM_011524539 XP_011522841 XM_011524540 XP_011522842 XM_011524541 XP_011522843 XM_011524542 XP_011522844 XM_011524543 XP_011522845 XM_011524544 XP_011522846 XM_011524545 XP_011522847 XM_011524546 XP_011522848 XR_934425 NM_001267727 NP_001254656 NM_014960 NP_055775 |
Function | Displays arylsulfatase activity at acidic pH with pseudosubstrates, such as p-nitrocatechol sulfate and also, but with lower activity, p-nitrophenyl sulfate and 4- methylumbelliferyl sulfate. {ECO:0000269|PubMed:18283100}. |
Subcellular Location | Lysosome {ECO:0000269|PubMed:12461688, ECO:0000269|PubMed:18283100}. Note=Previously observed endoplasmic reticulum localization is most likely due to folding/maturation problems for overexpressed proteins. |
Tissue Specificity | Widely expressed, with very low expression in brain, lung, heart and skeletal muscle. {ECO:0000269|PubMed:12461688, ECO:0000269|PubMed:18283100}. |
Top Pathways | Lysosome |
Arylsulfatase G CRISPR/Cas9 KO Plasmid (h) - sc-416756 from Santa Cruz Biotechnology
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Arylsulfatase G HDR Plasmid (h) - sc-416756-HDR from Santa Cruz Biotechnology
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Arylsulfatase G Double Nickase Plasmid (h) - sc-416756-NIC from Santa Cruz Biotechnology
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Arylsulfatase G Double Nickase Plasmid (h2) - sc-416756-NIC-2 from Santa Cruz Biotechnology
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Arylsulfatase G CRISPR Activation Plasmid (h) - sc-416756-ACT from Santa Cruz Biotechnology
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Arylsulfatase G CRISPR Activation Plasmid (h2) - sc-416756-ACT-2 from Santa Cruz Biotechnology
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Arylsulfatase G Lentiviral Activation Particles (h) - sc-416756-LAC from Santa Cruz Biotechnology
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Arylsulfatase G Lentiviral Activation Particles (h2) - sc-416756-LAC-2 from Santa Cruz Biotechnology
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Arylsulfatase G siRNA (h) - sc-93683 from Santa Cruz Biotechnology
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Arylsulfatase G shRNA Plasmid (h) - sc-93683-SH from Santa Cruz Biotechnology
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Arylsulfatase G shRNA (h) Lentiviral Particles - sc-93683-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU097871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3544 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3544 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03187 from Sigma-Aldrich
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ARSG siRNA (Human) - CRH7856 from Cohesion Biosciences
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ARSG - MBS8224603 from MyBioSource
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shRNA set against Human ARSG (NM_014960.4) - SHH240874 from Creative biogene
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Human ARSG siRNA - orb268358 from Biorbyt
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ARSG shRNA Plasmid (Human) - CHH7856 from Cohesion Biosciences
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ARSG miRNA 3'UTR clone - MiUTR3H-10962 from Creative biogene
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