HSD11B2

Gene Symbol	HSD11B2
Entrez Gene	3291
Alt Symbol	AME, AME1, HSD11K, HSD2, SDR9C3
Species	Human
Gene Type	protein-coding
Description	hydroxysteroid (11-beta) dehydrogenase 2
Other Description	-HSD11 type II|11-DH2|11-beta-HSD2|11-beta-hydroxysteroid dehydrogenase type 2|11-beta-hydroxysteroid dehydrogenase type II|NAD-dependent 11-beta-hydroxysteroid dehydrogenase|corticosteroid 11-beta-dehydrogenase isozyme 2|short chain dehydrogenase/reductase family 9C member 3
Swissprots	Q9UCW8 Q9UC50 Q8N439 Q9UCW6 A7LB28 P80365 Q9UCW5 C5HTY7 Q9UCW7 Q13194 Q96QN8 Q9UC51 Q6P2G9
Accessions	AAB48544 AAD14324 AAK91586 ABS29267 ACS13714 EAW83134 P80365 BC036780 AAH36780 BC064536 AAH64536 U14631 AAA91969 U26726 AAC50356 NM_000196 NP_000187
Function	Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Subcellular Location	Microsome {ECO:0000269|PubMed:17314322}. Endoplasmic reticulum {ECO:0000269|PubMed:17314322}.
Tissue Specificity	Found in placenta, kidney, pancreas, prostate, ovary, small intestine and colon.
Top Pathways	Steroid hormone biosynthesis, Aldosterone-regulated sodium reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HSD11B2 full length protein - ab132442 from Abcam Category Protein Source Wheat germ Species Human

Human HSD11B2 protein fragment - ab114569 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human HSD11B2 Protein - H00003291-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human HSD11B2 Protein - H00003291-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HSD11B2-Antibody-Center-Blocking-Peptide - BP9764c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HSD11B2 protein - orb245867 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

HSD11B2 Blocking Peptide - 33R-2718 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

11-beta HSD2 / HSD11B2 - H00003291-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

11-beta HSD2 / HSD11B2 - H00003291-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

11-beta HSD2 / HSD11B2 - H00003291-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

11-beta HSD2 / HSD11B2 - H00003291-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HSD11B2 fusion protein - ag5146 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human HSD11B2 - HSD11B2-27734TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human HSD11B2, GST-tagged - HSD11B2-13952H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human HSD11B2, GST-tagged - HSD11B2-13953H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant 11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2) - RPF183Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant 11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2) - RPF183Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant 11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2) - RPF183Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Corticosteroid 11-beta-dehydrogenase isozyme 2(HSD11B2) - CSB-EP010765HU CSB-BP010765HU CSB-MP010765HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Corticosteroid 11-beta-dehydrogenase isozyme 2(HSD11B2) - CSB-YP010765HU from Cusabio Category Protein Source Yeast Species Human

11-Beta-Hydroxysteroid Dehydrogenase Type 2, Recombinant Protein - MBS2031421 from MyBioSource Category Protein Prices $185.00, $390.00, $605.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

HSD11B2 Protein - abx164926 from Abbexa Category Protein Species Human, Mouse, Rat

11-beta HSD2 / HSD11B2 - TP307796 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human HSD11B2 protein, MYC/DDK-tagged - HSD11B2-13951H from Creative Biomart Category Protein Source HEK293 Species Human

HSD11B2 Recombinant Protein Antigen - NBP2-37954PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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