| Gene Symbol |
POLL
|
| Entrez Gene |
27343
|
| Alt Symbol |
BETAN, POLKAPPA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
polymerase (DNA directed), lambda
|
| Other Description |
DNA polymerase beta-2|DNA polymerase beta-N|DNA polymerase kappa|DNA polymerase lambda
|
| Swissprots |
Q9UGP5 Q9HA10 Q6NUM2 D3DR76 Q9BTN8 Q5JQP5 Q9HB35
|
| Accessions |
AAM77696 CAE90392 EAW49757 EAW49758 EAW49759 EAW49760 EAW49761 EAW49762 EAW49763 EAW49764 EAW49765 EAW49766 EAW49767 EAW49768 Q9UGP5 AF161019 AAF27541 AF218027 AAG17269 AF283478 AAG22519 AJ131890 CAB65074 AJ844641 CAH59753 AJ844642 CAH59754 AK021600 BAB13852 AK022476 BAB14050 AK091106 AK094956 AK127896 BAG54595 AK128521 AK292225 BAF84914 AK293421 BAG56928 AK293602 BAG57066 AK293657 BAH11560 AK300862 BAG62511 AL702021 AY302442 AAQ74388 BC003548 AAH03548 BC068529 AAH68529 BI906881 DA107389 DC296090 DC379162 DC409528 XM_006717775 XP_006717838 XM_006717776 XP_006717839 XM_006717777 XP_006717840 XM_006717778 XP_006717841 XM_011539650 XP_011537952 XM_011539651 XP_011537953 XM_011539652 XP_011537954 XM_011539653 XP_011537955 XM_011539654 XP_011537956 XM_011539655 XP_011537957 XM_011539656 XP_011537958 XM_011539657 XP_011537959 XM_011539658 XP_011537960 XM_011539659 XP_011537961 XM_011539660 XP_011537962 XM_011539661 XP_011537963 XM_011539662 XP_011537964 XM_011539663 XP_011537965 XM_011539664 XP_011537966 XM_011539665 XP_011537967 XM_011539666 XP_011537968 XM_011539667 XP_011537969 NM_001174084 NP_001167555 NM_001174085 NP_001167556 NM_001308382 NP_001295311 NM_013274 NP_037406 NR_033406
|
| Function |
Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. {ECO:0000269|PubMed:11457865, ECO:0000269|PubMed:15537631}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Expressed in a number of tissues. Abundant in testis.
|
| Top Pathways |
Base excision repair, Non-homologous end-joining
|