POLL

Gene Symbol POLL
Entrez Gene 27343
Alt Symbol BETAN, POLKAPPA
Species Human
Gene Type protein-coding
Description polymerase (DNA directed), lambda
Other Description DNA polymerase beta-2|DNA polymerase beta-N|DNA polymerase kappa|DNA polymerase lambda
Swissprots Q9UGP5 Q9HA10 Q6NUM2 D3DR76 Q9BTN8 Q5JQP5 Q9HB35
Accessions AAM77696 CAE90392 EAW49757 EAW49758 EAW49759 EAW49760 EAW49761 EAW49762 EAW49763 EAW49764 EAW49765 EAW49766 EAW49767 EAW49768 Q9UGP5 AF161019 AAF27541 AF218027 AAG17269 AF283478 AAG22519 AJ131890 CAB65074 AJ844641 CAH59753 AJ844642 CAH59754 AK021600 BAB13852 AK022476 BAB14050 AK091106 AK094956 AK127896 BAG54595 AK128521 AK292225 BAF84914 AK293421 BAG56928 AK293602 BAG57066 AK293657 BAH11560 AK300862 BAG62511 AL702021 AY302442 AAQ74388 BC003548 AAH03548 BC068529 AAH68529 BI906881 DA107389 DC296090 DC379162 DC409528 XM_006717775 XP_006717838 XM_006717776 XP_006717839 XM_006717777 XP_006717840 XM_006717778 XP_006717841 XM_011539650 XP_011537952 XM_011539651 XP_011537953 XM_011539652 XP_011537954 XM_011539653 XP_011537955 XM_011539654 XP_011537956 XM_011539655 XP_011537957 XM_011539656 XP_011537958 XM_011539657 XP_011537959 XM_011539658 XP_011537960 XM_011539659 XP_011537961 XM_011539660 XP_011537962 XM_011539661 XP_011537963 XM_011539662 XP_011537964 XM_011539663 XP_011537965 XM_011539664 XP_011537966 XM_011539665 XP_011537967 XM_011539666 XP_011537968 XM_011539667 XP_011537969 NM_001174084 NP_001167555 NM_001174085 NP_001167556 NM_001308382 NP_001295311 NM_013274 NP_037406 NR_033406
Function Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. {ECO:0000269|PubMed:11457865, ECO:0000269|PubMed:15537631}.
Subcellular Location Nucleus.
Tissue Specificity Expressed in a number of tissues. Abundant in testis.
Top Pathways Base excision repair, Non-homologous end-joining

DNA pol λ (E-11) - sc-373844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DNA pol λ (E-11): sc-373844. Western blot analysis of DNA pol λ expression in A549 (A), MCF7 (B) and HeLa (C) whole cell lysates and A549 (D) and MCF7 (E) nuclear extracts.

DNA pol λ (N-12) - sc-21530 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DNA pol λ (H-172) - sc-48812 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DNA pol λ (H-172): sc-48812. Western blot analysis of DNA pol λ expression in A549 whole cell lysate.

Anti-DNA Polymerase lambda antibody - ab5954 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab5954 at 5ug/ml staining DNA Polymerase lambda in human small intestine tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). A AP-staining procedure was used for detection.

Anti-DNA Polymerase lambda antibody - ab82919 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DNA Polymerase lambda antibody (ab82919) at 1 µg/ml + fetal brain lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-DNA Polymerase lambda antibody - ab84750 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84750 at 1/250 dilution staining DNA Polymerase lambda in human prostate nodular hypertrophy by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

Anti-DNA Polymerase lambda antibody - ab65146 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DNA Polymerase lambda antibody (ab65146) at 1/500 dilutionLane 1 : 293 cell extractLane 2 : 293 cell extract with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-DNA Polymerase lambda antibody - ab103234 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-DNA Polymerase lambda antibody (ab103234) at 1/50 dilution + HepG2 cell lysate at 35 µg

Anti-DNA Polymerase lambda antibody [EPR7519(2)] - ab172974 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7519(2)
All lanes : Anti-DNA Polymerase lambda antibody [EPR7519(2)] (ab172974) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HeLa cell lysateLane 3 : HepG2 cell lysateLysates/proteins at 10 µg per lane.

Anti-POLL / DNA Polymerase Lambda Antibody (aa150-200) - LS-C288429 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-POLL / DNA Polymerase Lambda Antibody (aa378-560) - LS-C311434 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-POLL / DNA Polymerase Lambda Antibody (aa427-476) - LS-C187204 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human MCF7. POLL antibody dilution 1.0 ug/ml.

Anti-POLL / DNA Polymerase Lambda Antibody (aa525-575) - LS-C286075 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse Pol Lambda by Immunohistochemistry. Sample: FFPE section of human stomach carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-Pol Lambda used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-POLL / DNA Polymerase Lambda Antibody (C-Terminus) - LS-C102574 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
POLL antibody LS-C102574 Western blot of Fetal Brain lysate.

Anti-POLL / DNA Polymerase Lambda Antibody (aa451-500) - LS-C119304 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from 293 cells, using DNA Polymerase lambda Antibody. The lane on the right is treated with the synthesized peptide.

Anti-POLL / DNA Polymerase Lambda Antibody (aa549-575) - LS-C163842 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of POLL Antibody in HepG2 cell line lysates (35 ug/lane). POLL (arrow) was detected using the purified antibody.

Anti-POLL / DNA Polymerase Lambda Antibody (aa525-575) - LS-C286562 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse Pol Lambda by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Pol Lambda used at a dilution of 1:250.

Anti-POLL / DNA Polymerase Lambda Antibody (aa563-575) IHC-plus™ - LS-B2284 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-POLL antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2284 concentration 5 ug/ml.

DNA Polymerase lambda Antibody - NB100-81665 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: DNA Polymerase lambda Antibody [NB100-81665] - Sample: FFPE section of human stomach carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti- Pol Lambda used at a dilution of 1:1,000 (1 ug/ml). Detection: DAB

DNA Polymerase lambda Antibody - NB100-1358 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: DNA Polymerase lambda Antibody [NB100-1358] - IHC analysis of DNA Polymerase lambda in paraffin embedded Human Small Intestine using this antibody at 5ug/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

DNA Polymerase lambda Antibody - NBP1-70837 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DNA Polymerase lambda Antibody [NBP1-70837] - Analysis of extracts from 293 cells, using DNA Polymerase lambda Antibody. The lane on the right is treated with the synthesized peptide.

DNA Polymerase lambda Antibody - NB100-81664 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA Polymerase lambda Antibody - bs-13020R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit

DNA Polymerase lambda Antibody, ALEXA FLUOR® 350 Conjugated - bs-13020R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit

DNA Polymerase lambda Antibody, ALEXA FLUOR® 488 Conjugated - bs-13020R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
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