| Gene Symbol |
NEUROG1
|
| Entrez Gene |
4762
|
| Alt Symbol |
AKA, Math4C, NEUROD3, bHLHa6, ngn1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neurogenin 1
|
| Other Description |
NGN-1|class A basic helix-loop-helix protein 6|neurogenic basic-helix-loop-helix protein|neurogenic differentiation 3|neurogenic differentiation factor 3|neurogenin-1
|
| Swissprots |
Q92886 Q96HE1 Q5U0Q9
|
| Accessions |
AAB37575 CAR95141 EAW62214 Q92886 AB593107 BAJ84047 AK314280 BAG36940 BC008687 AAH08687 BC028226 AAH28226 BT019366 AAV38173 DQ891529 ABM82455 DQ894718 ABM85644 NM_006161 NP_006152
|
| Function |
Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Expression restricted to the embryonic nervous system.
|
| Top Pathways |
Signaling pathways regulating pluripotency of stem cells
|
![Western Blot: Neurogenin 1 Overexpression Lysate (Adult Normal) [NBL1-13602] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Neurogenin 1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5540_Neurogenin%25201%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13602-img0002.jpg)