Gene Symbol | NEUROG1 |
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Entrez Gene | 4762 |
Alt Symbol | AKA, Math4C, NEUROD3, bHLHa6, ngn1 |
Species | Human |
Gene Type | protein-coding |
Description | neurogenin 1 |
Other Description | NGN-1|class A basic helix-loop-helix protein 6|neurogenic basic-helix-loop-helix protein|neurogenic differentiation 3|neurogenic differentiation factor 3|neurogenin-1 |
Swissprots | Q92886 Q96HE1 Q5U0Q9 |
Accessions | AAB37575 CAR95141 EAW62214 Q92886 AB593107 BAJ84047 AK314280 BAG36940 BC008687 AAH08687 BC028226 AAH28226 BT019366 AAV38173 DQ891529 ABM82455 DQ894718 ABM85644 NM_006161 NP_006152 |
Function | Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expression restricted to the embryonic nervous system. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
Neurogenin 1 CRISPR/Cas9 KO Plasmid (h) - sc-407618 from Santa Cruz Biotechnology
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Neurogenin 1 HDR Plasmid (h) - sc-407618-HDR from Santa Cruz Biotechnology
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Neurogenin 1 Double Nickase Plasmid (h) - sc-407618-NIC from Santa Cruz Biotechnology
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Neurogenin 1 Double Nickase Plasmid (h2) - sc-407618-NIC-2 from Santa Cruz Biotechnology
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Neurogenin 1 CRISPR Activation Plasmid (h) - sc-407618-ACT from Santa Cruz Biotechnology
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Neurogenin 1 CRISPR Activation Plasmid (h2) - sc-407618-ACT-2 from Santa Cruz Biotechnology
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Neurogenin 1 Lentiviral Activation Particles (h) - sc-407618-LAC from Santa Cruz Biotechnology
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Neurogenin 1 Lentiviral Activation Particles (h2) - sc-407618-LAC-2 from Santa Cruz Biotechnology
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Neurogenin 1 siRNA (h) - sc-106790 from Santa Cruz Biotechnology
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Neurogenin 1 shRNA Plasmid (h) - sc-106790-SH from Santa Cruz Biotechnology
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Neurogenin 1 shRNA (h) Lentiviral Particles - sc-106790-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN15228 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15228 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05765 from Sigma-Aldrich
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NEUROG1 siRNA (Human) - CRH3162 from Cohesion Biosciences
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Neurogenin-1 RNAi - H00004762-R01 from Novus Biologicals
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shRNA set against Human NEUROG1 (NM_006161.2) - SHH351600 from Creative biogene
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NEUROG1 shRNA Plasmid (Human) - CHH3162 from Cohesion Biosciences
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NEUROG1 miRNA 3'UTR clone - MiUTR1H-06729 from Creative biogene
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