Gene Symbol |
PROKR2
|
Entrez Gene |
128674
|
Alt Symbol |
GPR73L1, GPR73b, GPRg2, HH3, KAL3, PKR2, dJ680N4.3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
prokineticin receptor 2
|
Other Description |
G protein-coupled receptor 73-like 1|PK-R2
|
Swissprots |
Q5TDY1 Q2M3C0 A5JUU1 Q9NTT0 Q8NFJ6
|
Accessions |
EAX10422 Q8NFJ6 AB084081 BAC24022 AF506288 AAM48128 AK289995 BAF82684 BC104959 AAI04960 BC104961 AAI04962 EF577398 ABQ52418 XM_005260663 XP_005260720 XM_011529159 XP_011527461 NM_144773 NP_658986
|
Function |
Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase.
|
Subcellular Location |
Cell membrane {ECO:0000269|PubMed:18826963}; Multi-pass membrane protein.
|
Tissue Specificity |
Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain.
|