Gene Symbol | PROKR2 |
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Entrez Gene | 128674 |
Alt Symbol | GPR73L1, GPR73b, GPRg2, HH3, KAL3, PKR2, dJ680N4.3 |
Species | Human |
Gene Type | protein-coding |
Description | prokineticin receptor 2 |
Other Description | G protein-coupled receptor 73-like 1|PK-R2 |
Swissprots | Q5TDY1 Q2M3C0 A5JUU1 Q9NTT0 Q8NFJ6 |
Accessions | EAX10422 Q8NFJ6 AB084081 BAC24022 AF506288 AAM48128 AK289995 BAF82684 BC104959 AAI04960 BC104961 AAI04962 EF577398 ABQ52418 XM_005260663 XP_005260720 XM_011529159 XP_011527461 NM_144773 NP_658986 |
Function | Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:18826963}; Multi-pass membrane protein. |
Tissue Specificity | Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain. |
PKR2 CRISPR/Cas9 KO Plasmid (h) - sc-405229 from Santa Cruz Biotechnology
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PKR2 HDR Plasmid (h) - sc-405229-HDR from Santa Cruz Biotechnology
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PKR2 Double Nickase Plasmid (h) - sc-405229-NIC from Santa Cruz Biotechnology
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PKR2 Double Nickase Plasmid (h2) - sc-405229-NIC-2 from Santa Cruz Biotechnology
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PKR2 CRISPR Activation Plasmid (h) - sc-405229-ACT from Santa Cruz Biotechnology
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PKR2 CRISPR Activation Plasmid (h2) - sc-405229-ACT-2 from Santa Cruz Biotechnology
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PKR2 Lentiviral Activation Particles (h) - sc-405229-LAC from Santa Cruz Biotechnology
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PKR2 Lentiviral Activation Particles (h2) - sc-405229-LAC-2 from Santa Cruz Biotechnology
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PKR2 siRNA (h) - sc-72363 from Santa Cruz Biotechnology
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PKR2 shRNA Plasmid (h) - sc-72363-SH from Santa Cruz Biotechnology
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PKR2 shRNA (h) Lentiviral Particles - sc-72363-V from Santa Cruz Biotechnology
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Prokineticin R2/PROKR2 RNAi - H00128674-R02 from Novus Biologicals
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MISSION® esiRNA - EHU139151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2538 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2538 from Sigma-Aldrich
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PROKR2 siRNA (Human) - CRJ4975 from Cohesion Biosciences
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shRNA set against Human PROKR2(NM_144773.2) - SHR142122 from Creative biogene
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Human PROKR2 siRNA - orb275476 from Biorbyt
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PROKR2 shRNA Plasmid (Human) - CHJ4975 from Cohesion Biosciences
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PROKR2 miRNA 3'UTR clone - MiUTR1H-08309 from Creative biogene
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