| Gene Symbol |
NXT1
|
| Entrez Gene |
29107
|
| Alt Symbol |
MTR2, P15
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nuclear transport factor 2-like export factor 1
|
| Other Description |
NTF2-like export factor 1|NTF2-related export protein 1|NTX2-like export factor1|NUTF-like export factor 1|protein p15
|
| Swissprots |
Q9UKK6
|
| Accessions |
EAX10163 Q9UKK6 AF156957 AAD54942 AK026360 BC000759 AAH00759 BC002687 AAH02687 BC003029 AAH03029 BC003410 AAH03410 XM_011529230 XP_011527532 NM_013248 NP_037380
|
| Function |
Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5. {ECO:0000269|PubMed:10567585, ECO:0000269|PubMed:10848583, ECO:0000269|PubMed:11259602, ECO:0000269|PubMed:19165146}.
|
| Subcellular Location |
Nucleus. Nucleus speckle {ECO:0000305}. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
|
| Top Pathways |
RNA transport, mRNA surveillance pathway, Ribosome biogenesis in eukaryotes, Influenza A
|