| Gene Symbol |
ANO7
|
| Entrez Gene |
50636
|
| Alt Symbol |
D-TMPP, DTMPP, IPCA-5, IPCA5, NGEP, PCANAP5, PCANAP5L, TMEM16G
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
anoctamin 7
|
| Other Description |
Dresden-transmembrane protein of the prostate|anoctamin-7|prostate cancer associated protein 5|transmembrane protein 16G
|
| Swissprots |
Q6IWH7 Q6IWH6
|
| Accessions |
Q6IWH7 AK057322 AY617079 AAT40139 AY617080 AAT40140 BC028162 AAH28162 BC038852 BC047903 BC156324 AAI56325 BC157069 AAI57070 CD672346 XM_011511256 XP_011509558 XM_011511257 XP_011509559 XM_011511258 XP_011509560 XM_011511259 XP_011509561 XM_011511260 XP_011509562 XM_011511261 XP_011509563 XM_011511262 XP_011509564 XM_011511263 XP_011509565 XM_011511264 XP_011509566 XM_011511265 XP_011509567 XM_011511266 XP_011509568 XM_011511267 XP_011509569 XM_011511268 XP_011509570 XM_011511269 XP_011509571 XM_011511270 XP_011509572 XM_011511271 XP_011509573 XM_011511272 XP_011509574 XM_011511273 XP_011509575 XR_922931 XR_922932 XR_922933 XR_922934 XR_922935 XR_922936 NM_001001666 NP_001001666 NM_001001891 NP_001001891
|
| Function |
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions. {ECO:0000250|UniProtKB:Q14AT5, ECO:0000269|PubMed:17308099}.
|
| Subcellular Location |
Isoform 1: Cell membrane; Multi-pass membrane protein. Cell junction. Endoplasmic reticulum. Note=Concentrates at sites of cell-cell contact. Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604.
|
| Tissue Specificity |
Specifically expressed in epithelial cells of the prostate (at protein level). {ECO:0000269|PubMed:14981236, ECO:0000269|PubMed:15761874, ECO:0000269|PubMed:17308099}.
|