Gene Symbol | ANO7 |
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Entrez Gene | 50636 |
Alt Symbol | D-TMPP, DTMPP, IPCA-5, IPCA5, NGEP, PCANAP5, PCANAP5L, TMEM16G |
Species | Human |
Gene Type | protein-coding |
Description | anoctamin 7 |
Other Description | Dresden-transmembrane protein of the prostate|anoctamin-7|prostate cancer associated protein 5|transmembrane protein 16G |
Swissprots | Q6IWH7 Q6IWH6 |
Accessions | Q6IWH7 AK057322 AY617079 AAT40139 AY617080 AAT40140 BC028162 AAH28162 BC038852 BC047903 BC156324 AAI56325 BC157069 AAI57070 CD672346 XM_011511256 XP_011509558 XM_011511257 XP_011509559 XM_011511258 XP_011509560 XM_011511259 XP_011509561 XM_011511260 XP_011509562 XM_011511261 XP_011509563 XM_011511262 XP_011509564 XM_011511263 XP_011509565 XM_011511264 XP_011509566 XM_011511265 XP_011509567 XM_011511266 XP_011509568 XM_011511267 XP_011509569 XM_011511268 XP_011509570 XM_011511269 XP_011509571 XM_011511270 XP_011509572 XM_011511271 XP_011509573 XM_011511272 XP_011509574 XM_011511273 XP_011509575 XR_922931 XR_922932 XR_922933 XR_922934 XR_922935 XR_922936 NM_001001666 NP_001001666 NM_001001891 NP_001001891 |
Function | Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium- activated chloride channel (CaCC) activity. May play a role in cell-cell interactions. {ECO:0000250|UniProtKB:Q14AT5, ECO:0000269|PubMed:17308099}. |
Subcellular Location | Isoform 1: Cell membrane; Multi-pass membrane protein. Cell junction. Endoplasmic reticulum. Note=Concentrates at sites of cell-cell contact. Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604. |
Tissue Specificity | Specifically expressed in epithelial cells of the prostate (at protein level). {ECO:0000269|PubMed:14981236, ECO:0000269|PubMed:15761874, ECO:0000269|PubMed:17308099}. |
NGEP CRISPR/Cas9 KO Plasmid (h) - sc-412078 from Santa Cruz Biotechnology
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NGEP HDR Plasmid (h) - sc-412078-HDR from Santa Cruz Biotechnology
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NGEP Double Nickase Plasmid (h) - sc-412078-NIC from Santa Cruz Biotechnology
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NGEP Double Nickase Plasmid (h2) - sc-412078-NIC-2 from Santa Cruz Biotechnology
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NGEP CRISPR Activation Plasmid (h) - sc-412078-ACT from Santa Cruz Biotechnology
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NGEP CRISPR Activation Plasmid (h2) - sc-412078-ACT-2 from Santa Cruz Biotechnology
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NGEP Lentiviral Activation Particles (h) - sc-412078-LAC from Santa Cruz Biotechnology
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NGEP Lentiviral Activation Particles (h2) - sc-412078-LAC-2 from Santa Cruz Biotechnology
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NGEP siRNA (h) - sc-94463 from Santa Cruz Biotechnology
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NGEP shRNA Plasmid (h) - sc-94463-SH from Santa Cruz Biotechnology
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NGEP shRNA (h) Lentiviral Particles - sc-94463-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN3247 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3247 from Sigma-Aldrich
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ANO7 siRNA (Human) - CRH9396 from Cohesion Biosciences
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ANO7 - MBS8207093 from MyBioSource
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shRNA set against Human ANO7 (NM_001001666.3) - SHH237366 from Creative biogene
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Human ANO7 siRNA - orb269898 from Biorbyt
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ANO7 shRNA Plasmid (Human) - CHH9396 from Cohesion Biosciences
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ANO7 miRNA 3'UTR clone - MiUTR1H-10510 from Creative biogene
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ANO7 miRNA 3'UTR clone - MiUTR1H-10511 from Creative biogene
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