PPP3CA

Gene Symbol	PPP3CA
Entrez Gene	5530
Alt Symbol	CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 3, catalytic subunit, alpha isozyme
Other Description	CAM-PRP catalytic subunit|calcineurin A alpha|calmodulin-dependent calcineurin A subunit alpha isoform|protein phosphatase 2B, catalytic subunit, alpha isoform|protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform|serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Swissprots	A1A441 A8W6Z8 B5BUA2 A8W6Z7 A8K3B7 Q8TAW9 Q08209
Accessions	EAX06123 EAX06124 EAX06125 Q08209 AB451338 BAG70152 AB451487 BAG70301 AK290532 BAF83221 AL353950 CAB89253 AM393486 CAL38363 AM393713 CAL38589 AW973358 AY904364 AAY17314 BC025714 AAH25714 BC098424 EU192652 ABW74484 EU192653 ABW74485 J05480 AAA35634 L14778 AAA02631 NM_000944 NP_000935 NM_001130691 NP_001124163 NM_001130692 NP_001124164
Function	Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. {ECO:0000269|PubMed:15671020, ECO:0000269|PubMed:17498738, ECO:0000269|PubMed:18838687}.
Subcellular Location	Cell membrane {ECO:0000250}. Cell membrane, sarcolemma {ECO:0000250}. Nucleus {ECO:0000250}. Note=Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle. {ECO:0000250}.
Top Pathways	Glucagon signaling pathway, Glutamatergic synapse, Dopaminergic synapse, Amphetamine addiction, Oxytocin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Calcineurin A full length protein - ab128554 from Abcam Category Protein Prices $235.00 Sizes 20 µg Source Baculovirus infected sf9 cells Species Human

Human Calcineurin A full length protein - ab101870 from Abcam Category Protein Prices $235.00, $866.00 Sizes 10 µg, 50 µg Source E. coli Species Human

PPP3CA / CCN1 / Calcineurin A Antibody Blocking Peptide - LS-E2680 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPP3CA / CCN1 / Calcineurin A Antibody Blocking Peptide - LS-E18486 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPP3CA / CCN1 / Calcineurin A Antibody Blocking Peptide - LS-E9595 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Calcineurin A Partial Recombinant Protein - H00005530-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Calcineurin A Protein - NBP1-50945 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 10 µg, 50 µg Source E. coli Species Human

Calcineurin A Recombinant Protein - P3563 from Novus Biologicals Category Protein Prices $549.00 Sizes 10 µg Species Human

Calcineurin A Peptide - P3305 from Novus Biologicals Category Peptide Species Human

Calcineurin A Peptide - P3304 from Novus Biologicals Category Peptide Species Human

PPP3CA-Antibody-C-term-Blocking-peptide - BP13757b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Calcineurin-PPP3CA-Antibody-C-term-Blocking-peptide - BP8463b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Calcineurin-PPP3CA-Antibody-N-term-Blocking-peptide - BP8463a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Calcineurin, CF - 3160-CA-020 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

PPP3CA Protein (OPPA02501) - OPPA02501 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 1 µg Source E. Coli

Human PPP3CA protein (His Tag) - orb139510 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Baculovirus-Insect Cells Species Human

Human PPP3CA protein - orb169071 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 1 μg, 5 μg, 50 μg Species Human

PPP3CA Blocking Peptide - 33R-6417 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PPP3CA Blocking Peptide - 33R-5289 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PPP3CA protein (His tag) - 80R-1620 from Fitzgerald Category Protein Prices $255.00 Sizes 10 µg Source E.coli

Human Calcineurin Protein - abx065654 from Abbexa Category Protein Source E.coli Species Human

PPP3CA / Calcineurin A (1-511, His-tag) - AR09801PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

PPP3CA / Calcineurin A (1-511, His-tag) - AR09801PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

PPP3CA / Calcineurin A - H00005530-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PPP3CA / Calcineurin A - H00005530-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

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