Gene Symbol |
CPPED1
|
Entrez Gene |
55313
|
Alt Symbol |
CSTP1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
calcineurin-like phosphoesterase domain containing 1
|
Other Description |
calcineurin-like phosphoesterase domain-containing protein 1|complete S transactivated protein 1|complete S-transactivated protein 1|serine/threonine-protein phosphatase CPPED1
|
Swissprots |
Q9H9M9 B4DQ68 Q9BRF8 Q9NUT6 Q6MZY9
|
Accessions |
EAW85121 EAW85122 Q9BRF8 AK002013 BAA92034 AK022710 BAB14194 AK093854 BAG52775 AK225359 AK225617 AK298662 BAG60830 AY553877 AAS64575 BC006289 AAH06289 BX092044 BX640805 CAE45887 DA387854 DB468489 HQ447818 ADQ32302 NM_001099455 NP_001092925 NM_018340 NP_060810
|
Function |
Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes. {ECO:0000269|PubMed:23799035, ECO:0000269|PubMed:23939394}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:23799035}.
|
Tissue Specificity |
Expressed in subcutaneous adipose tissue. {ECO:0000269|PubMed:23939394}.
|