Gene Symbol | CPPED1 |
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Entrez Gene | 55313 |
Alt Symbol | CSTP1 |
Species | Human |
Gene Type | protein-coding |
Description | calcineurin-like phosphoesterase domain containing 1 |
Other Description | calcineurin-like phosphoesterase domain-containing protein 1|complete S transactivated protein 1|complete S-transactivated protein 1|serine/threonine-protein phosphatase CPPED1 |
Swissprots | Q9H9M9 B4DQ68 Q9BRF8 Q9NUT6 Q6MZY9 |
Accessions | EAW85121 EAW85122 Q9BRF8 AK002013 BAA92034 AK022710 BAB14194 AK093854 BAG52775 AK225359 AK225617 AK298662 BAG60830 AY553877 AAS64575 BC006289 AAH06289 BX092044 BX640805 CAE45887 DA387854 DB468489 HQ447818 ADQ32302 NM_001099455 NP_001092925 NM_018340 NP_060810 |
Function | Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes. {ECO:0000269|PubMed:23799035, ECO:0000269|PubMed:23939394}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:23799035}. |
Tissue Specificity | Expressed in subcutaneous adipose tissue. {ECO:0000269|PubMed:23939394}. |
CPPED1 CRISPR/Cas9 KO Plasmid (h) - sc-412514 from Santa Cruz Biotechnology
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CPPED1 HDR Plasmid (h) - sc-412514-HDR from Santa Cruz Biotechnology
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CPPED1 Double Nickase Plasmid (h) - sc-412514-NIC from Santa Cruz Biotechnology
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CPPED1 Double Nickase Plasmid (h2) - sc-412514-NIC-2 from Santa Cruz Biotechnology
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CPPED1 CRISPR Activation Plasmid (h) - sc-412514-ACT from Santa Cruz Biotechnology
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CPPED1 CRISPR Activation Plasmid (h2) - sc-412514-ACT-2 from Santa Cruz Biotechnology
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CPPED1 Lentiviral Activation Particles (h) - sc-412514-LAC from Santa Cruz Biotechnology
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CPPED1 Lentiviral Activation Particles (h2) - sc-412514-LAC-2 from Santa Cruz Biotechnology
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CPPED1 siRNA (h) - sc-93144 from Santa Cruz Biotechnology
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CPPED1 shRNA Plasmid (h) - sc-93144-SH from Santa Cruz Biotechnology
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CPPED1 shRNA (h) Lentiviral Particles - sc-93144-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU010271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6519 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6519 from Sigma-Aldrich
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CPPED1 siRNA (Human) - CRJ0646 from Cohesion Biosciences
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CPPED1 - MBS8234319 from MyBioSource
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shRNA set against Human CPP (NM_018340.2) - SHH268873 from Creative biogene
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shRNA set against Human FLJ11151(NM_018340.2) - SHG205459 from Creative biogene
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CPPED1 shRNA Plasmid (Human) - CHJ0646 from Cohesion Biosciences
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CPPED1 miRNA 3'UTR clone - MiUTR1H-03680 from Creative biogene
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