DBN1

Gene Symbol	DBN1
Entrez Gene	1627
Alt Symbol	D0S117E
Species	Human
Gene Type	protein-coding
Description	drebrin 1
Other Description	developmentally-regulated brain protein|drebrin|drebrin E|drebrin E2|drebrin-1
Swissprots	B2RBG0 A8MV58 Q9UFZ5 Q16643
Accessions	EAW84989 EAW84990 EAW84991 EAW84992 EAW84993 Q16643 AI683844 AK094125 BAG52819 AK225523 AK295295 BAH12026 AK314645 BAG37207 AL110225 CAB53683 AM393436 CAL38314 AW950551 BC000283 AAH00283 BC007281 AAH07281 BC007567 AAH07567 BC114553 BF205663 D17530 BAA04480 DA245346 DR158741 U00802 AAA16256 XM_005265827 XP_005265884 XM_005265828 XP_005265885 XM_005265829 XP_005265886 XM_006714826 XP_006714889 XM_011534446 XP_011532748 XM_011534447 XP_011532749 NM_004395 NP_004386 NM_080881 NP_543157
Function	Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS. {ECO:0000269|PubMed:20215400}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20215400}. Cytoplasm, cell cortex {ECO:0000269|PubMed:20215400}. Cell junction {ECO:0000269|PubMed:20215400}. Note=In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC).
Tissue Specificity	Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas. Expressed in peripheral blood lymphocytes, including T-cells (at protein level). {ECO:0000269|PubMed:20215400}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Drebrin A Antibody - 12243 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

Drebrin (pan) Antibody - 5052 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

Drebrin (B-6) - sc-393097 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Drebrin (C-8) - sc-374269 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Drebrin (H-156) - sc-366274 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Drebrin (N-12) - sc-30394 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Drebrin (S-16) - sc-30396 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Drebrin (V-20) - sc-30395 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Drebrin antibody [EPR12634] - ab178408 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR12634

Anti-Drebrin antibody [EPR12640(B)] - ab176318 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR12640(B)

Anti-DBN1 / Drebrin Antibody (aa632-649) - LS-C65042 from LifeSpan Bioscience Prices $650.00 Sizes 250 µl Host Mouse Clonality Monoclonal

Anti-DBN1 / Drebrin Antibody - LS-C65041 from LifeSpan Bioscience Prices $485.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-DBN1 / Drebrin Antibody (aa254-272) - LS-C65040 from LifeSpan Bioscience Prices $710.00 Sizes 100 µl Host Guinea Pig Clonality Polyclonal

Anti-DBN1 / Drebrin Antibody (aa324-343) - LS-C65039 from LifeSpan Bioscience Prices $710.00 Sizes 100 µl Host Guinea Pig Clonality Polyclonal

Anti-DBN1 / Drebrin Antibody (aa632-649) - LS-C65043 from LifeSpan Bioscience Prices $575.00 Sizes 5 ml Host Mouse Clonality Monoclonal

Anti-DBN1 / Drebrin Antibody (clone M2F6) - LS-C85074 from LifeSpan Bioscience Prices $710.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone M2F6

Anti-DBN1 / Drebrin Antibody (aa632-649, clone MX823) - LS-C85075 from LifeSpan Bioscience Prices $695.00 Sizes 250 µl Host Mouse Clonality Monoclonal Clone MX823

Anti-DBN1 / Drebrin Antibody (aa324-343) - LS-C86060 from LifeSpan Bioscience Prices $695.00 Sizes 100 µl Host Guinea Pig Clonality Polyclonal

Anti-DBN1 / Drebrin Antibody (aa254-272) - LS-C86061 from LifeSpan Bioscience Prices $695.00 Sizes 100 µl Host Guinea Pig Clonality Polyclonal

Anti-DBN1 / Drebrin Antibody (Internal) - LS-C125497 from LifeSpan Bioscience Prices $485.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-DBN1 / Drebrin Antibody - LS-C193959 from LifeSpan Bioscience Prices $905.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-DBN1 / Drebrin Antibody (aa1-326, clone DBN-N-03) - LS-C204502 from LifeSpan Bioscience Prices $290.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone DBN-N-03

Anti-DBN1 / Drebrin Antibody (aa1-326, clone DBN-N-03, PE) - LS-C204478 from LifeSpan Bioscience Prices $315.00 Sizes 100 tst Host Mouse Clonality Monoclonal Clone DBN-N-03

Anti-DBN1 / Drebrin Antibody (clone 2E11) - LS-C197024 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2E11

Anti-DBN1 / Drebrin Antibody - LS-C334664 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

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