Gene Symbol |
ATP5G2
|
Entrez Gene |
517
|
Alt Symbol |
ATP5A
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
|
Other Description |
ATP synthase F(0) complex subunit C2, mitochondrial|ATP synthase c subunit|ATP synthase lipid-binding protein, mitochondrial|ATP synthase proteolipid P2|ATP synthase proton-transporting mitochondrial F(0) complex subunit C2|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)|ATPase protein 9|ATPase subunit C|mitochondrial ATP synthase, subunit C (subunit 9)
|
Swissprots |
B3KQQ6 Q06055
|
Accessions |
CAA49533 EAW96725 EAW96726 Q06055 AK075351 BAG52118 AK130971 AK311357 AV737582 BC013839 BC020826 AAH20826 BF337574 BG217012 BQ682406 BX348847 D13119 BAA02421 D28402 BAA05768 DQ891367 ABM82293 DQ894547 ABM85473 H83751 M16439 AAA51804 XM_011538486 XP_011536788 NM_001002031 NP_001002031 NM_005176 NP_005167
|
Function |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
|
Subcellular Location |
Mitochondrion membrane; Multi-pass membrane protein.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Oxidative phosphorylation
|