Gene Symbol | ATP5G2 |
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Entrez Gene | 517 |
Alt Symbol | ATP5A |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
Other Description | ATP synthase F(0) complex subunit C2, mitochondrial|ATP synthase c subunit|ATP synthase lipid-binding protein, mitochondrial|ATP synthase proteolipid P2|ATP synthase proton-transporting mitochondrial F(0) complex subunit C2|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)|ATPase protein 9|ATPase subunit C|mitochondrial ATP synthase, subunit C (subunit 9) |
Swissprots | B3KQQ6 Q06055 |
Accessions | CAA49533 EAW96725 EAW96726 Q06055 AK075351 BAG52118 AK130971 AK311357 AV737582 BC013839 BC020826 AAH20826 BF337574 BG217012 BQ682406 BX348847 D13119 BAA02421 D28402 BAA05768 DQ891367 ABM82293 DQ894547 ABM85473 H83751 M16439 AAA51804 XM_011538486 XP_011536788 NM_001002031 NP_001002031 NM_005176 NP_005167 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. |
Subcellular Location | Mitochondrion membrane; Multi-pass membrane protein. |
Top Pathways | Alzheimer's disease, Huntington's disease, Oxidative phosphorylation |
ATP5G2 CRISPR/Cas9 KO Plasmid (h) - sc-403484 from Santa Cruz Biotechnology
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ATP5G2 HDR Plasmid (h) - sc-403484-HDR from Santa Cruz Biotechnology
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ATP5G2 Double Nickase Plasmid (h) - sc-403484-NIC from Santa Cruz Biotechnology
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ATP5G2 Double Nickase Plasmid (h2) - sc-403484-NIC-2 from Santa Cruz Biotechnology
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ATP5G2 CRISPR Activation Plasmid (h) - sc-403484-ACT from Santa Cruz Biotechnology
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ATP5G2 CRISPR Activation Plasmid (h2) - sc-403484-ACT-2 from Santa Cruz Biotechnology
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ATP5G2 Lentiviral Activation Particles (h) - sc-403484-LAC from Santa Cruz Biotechnology
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ATP5G2 Lentiviral Activation Particles (h2) - sc-403484-LAC-2 from Santa Cruz Biotechnology
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ATP5G2 siRNA (h) - sc-95864 from Santa Cruz Biotechnology
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ATP5G2 shRNA Plasmid (h) - sc-95864-SH from Santa Cruz Biotechnology
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ATP5G2 shRNA (h) Lentiviral Particles - sc-95864-V from Santa Cruz Biotechnology
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ATP5G2 RNAi - H00000517-R03 from Novus Biologicals
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ATP5G2 RNAi - H00000517-R04 from Novus Biologicals
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MISSION® esiRNA - EHU112831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3702 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3702 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00238 from Sigma-Aldrich
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ATP5G2 siRNA (Human) - CRH0358 from Cohesion Biosciences
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ATP5G2 - MBS8224226 from MyBioSource
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shRNA set against Human ATP5G2 (NM_001002031.2) - SHH242818 from Creative biogene
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shRNA set against Human ATP5G2(NM_001002031.2) - SHG082441 from Creative biogene
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shRNA set against Human ATP5G2(NM_005176.5) - SHG082469 from Creative biogene
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ATP5G2 shRNA Plasmid (Human) - CHH0358 from Cohesion Biosciences
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ATP5G2 miRNA 3'UTR clone - MiUTR1H-00697 from Creative biogene
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ATP5G2 miRNA 3'UTR clone - MiUTR3H-05765 from Creative biogene
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