ANGPT2

Gene Symbol	ANGPT2
Entrez Gene	285
Alt Symbol	AGPT2, ANG2
Species	Human
Gene Type	protein-coding
Description	angiopoietin 2
Other Description	ANG-2|Tie2-ligand|angiopoietin-2|angiopoietin-2B|angiopoietin-2a
Swissprots	Q9P2Y7 B7ZLM7 Q9NRR7 A0AV38 A8K205 O15123
Accessions	AAT69979 CAK96154 EAW80472 EAW80473 EAW80474 O15123 AB009865 BAA95590 AF004327 AAB63190 AF187858 AAF76526 AF218015 AAG17257 AJ289780 CAC08179 AJ289781 CAC08180 AK075219 AK225698 AK290070 BAF82759 AK310171 AK312541 BAG35440 BC022490 BC126200 AAI26201 BC126202 AAI26203 BC143902 AAI43903 DA829327 HQ258258 ADR83012 NM_001118887 NP_001112359 NM_001118888 NP_001112360 NM_001147 NP_001138
Function	Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. {ECO:0000269|PubMed:15284220, ECO:0000269|PubMed:19116766, ECO:0000269|PubMed:19223473, ECO:0000269|PubMed:9204896}.
Subcellular Location	Secreted.
Top Pathways	PI3K-Akt signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Angiopoietin 2 (ANG2) Human ELISA Kit - ab99971 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 10 pg/ml Range 4.12 pg/ml - 3000 pg/ml

Human Angiopoietin-2 ELISA Kit - RAB0016 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human Angiopoietin-2 Quantikine ELISA Kit - DANG20 from R&D Systems Category ELISA Kit Prices $519.00, $2,491.00, $16,868.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 21.3 pg/mL Range 46.9 - 3,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva)

Human Angiopoietin-2 Quantikine PharmPak (50 Plates) - PDANG20 from R&D Systems Category ELISA Kit Sensitivity 21.3 pg/mL Range 46.9 - 3,000 pg/mL (Serum, Heparin Plasma, Saliva, Cell Culture Supernates, EDTA Plasma)

Human Angiopoietin-2 Quantikine SixPak (6 Plates) - SANG20 from R&D Systems Category ELISA Kit Sensitivity 21.3 pg/mL Range 46.9 - 3,000 pg/mL (Serum, Heparin Plasma, Saliva, Cell Culture Supernates, EDTA Plasma)

Human Angiopoietin-2 DuoSet ELISA - DY623 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 93.80 - 6,000 pg/mL

Mouse/Rat Angiopoietin-2 Quantikine ELISA Kit - MANG20 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 4.98 pg/mL Range 39.1 - 2,500 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma)

Quantikine Immunoassay Control Set 832 Human Angiopoietin-2 - QC43 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Human Angiopoietin 2 ELISA kit - 55R-2192 from Fitzgerald Category ELISA Kit Prices $545.00 Sizes 96 tests

Angiopoietin-2 ELISA Kit (Human) : 96 Wells (OKAG00195) - OKAG00195 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 94 pg/mL Range 94-6,000 pg/mL

Human Angiopoietin 2 ELISA Kit - abx052164 from Abbexa Category ELISA Kit Sensitivity 0.6 ng/L Range 3 ng/L - 150 ng/L

Human Angiopoietin 2 ELISA Kit - abx150648 from Abbexa Category ELISA Kit Sensitivity 0.074 ng/ml Range 0.188 ng/ml - 12 ng/ml

Human Angiopoietin-2 ELISA Kit - abx056010 from Abbexa Category ELISA Kit

ANG II, Human, ELISA Kit - BEK1008 from ARP American Research Products Category ELISA Kit Prices $529.00 Sizes 96 t Sensitivity < 10 pg/ml Range 8 pg/ml-150 pg/ml

Angiopoietin 2, ANG2, Human, ELISA Kit - E-EL-H0008 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 28.125 Range 46.875-3000pg/mL

Angiopoietin 2 (ANGPT2), Human, ELISA Kit - SEA009Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.37ng/mL Range 0.78 -50ng/mL

Angiopoietin 2, ANG-2, Human, ELISA Kit - CSB-E04500h from ARP American Research Products Category ELISA Kit Prices $366.00, $496.00, $497.00, $499.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.39 pg/ml Range 1.56 pg/ml-100 pg/ml

Angiopoietin 2, Human, ELISA Kit - E01A0503 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1 ng/mL Range 1-25ng/mL

Angiopoietin-2, ANGPT2, Human, ELISA Kit - E0009h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 0.156-10 ng/mL

Angiopoietin 2, ANG2, Mouse, ELISA Kit - E-EL-M0098 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Angiopoietin 2, ANG2, Rat, ELISA Kit - E-EL-R0125 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Angiopoietin 2, ANG2, Rabbit, ELISA Kit - E-EL-RB0379 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Angiopoietin 2, ANG2, Chicken, ELISA Kit - E-EL-Ch0547 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Angiopoietin 2, ANG2, Porcine, ELISA Kit - E-EL-P0905 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Angiopoietin 2, ANG2, Sheep, ELISA Kit - E-EL-S0711 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Search more