ANGPT2

Gene Symbol	ANGPT2
Entrez Gene	285
Alt Symbol	AGPT2, ANG2
Species	Human
Gene Type	protein-coding
Description	angiopoietin 2
Other Description	ANG-2|Tie2-ligand|angiopoietin-2|angiopoietin-2B|angiopoietin-2a
Swissprots	Q9P2Y7 B7ZLM7 Q9NRR7 A0AV38 A8K205 O15123
Accessions	AAT69979 CAK96154 EAW80472 EAW80473 EAW80474 O15123 AB009865 BAA95590 AF004327 AAB63190 AF187858 AAF76526 AF218015 AAG17257 AJ289780 CAC08179 AJ289781 CAC08180 AK075219 AK225698 AK290070 BAF82759 AK310171 AK312541 BAG35440 BC022490 BC126200 AAI26201 BC126202 AAI26203 BC143902 AAI43903 DA829327 HQ258258 ADR83012 NM_001118887 NP_001112359 NM_001118888 NP_001112360 NM_001147 NP_001138
Function	Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. {ECO:0000269|PubMed:15284220, ECO:0000269|PubMed:19116766, ECO:0000269|PubMed:19223473, ECO:0000269|PubMed:9204896}.
Subcellular Location	Secreted.
Top Pathways	PI3K-Akt signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Angiopoietin-2 Gene cDNA Clone - orb141798 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-ANGPT2-cDNA-Clone - DC14366 from Abgent, a WuXi AppTec company Prices $669.60 Sizes 10 µg Species Human Accession BC126200

ANGPT2 - MBS1277513 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC126200

Human ANGPT2 cDNA clone(NM_001118887.1) - CDFH000778 from Creative Biomart Species Human Accession NM_001118887.1

Human ANGPT2 cDNA clone(NM_001118888.1) - CDFH000779 from Creative Biomart Species Human Accession NM_001118888.1

Human ANGPT2 ORF clone(NM_001147.2) - CDCL182689 from Creative Biomart Species Human Accession NM_001147.2

Human ANGPT2 ORF Clone(NM_001118887.1) - CDCR348206 from Creative Biomart Species Human Accession NM_001118887.1

Human ANGPT2 ORF Clone(NM_001118887.1) - CDCR348207 from Creative Biomart Species Human Accession NM_001118887.1

Human ANGPT2 ORF Clone(NM_001118888.1) - CDCR348208 from Creative Biomart Species Human Accession NM_001118888.1

Human ANGPT2 ORF Clone(NM_001118888.1) - CDCR348209 from Creative Biomart Species Human Accession NM_001118888.1

Human ANGPT2 ORF Clone(NM_001147.2) - CDCL153798 from Creative Biomart Species Human Accession NM_001147.2

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone in cloning vector - HG10691-G from Sino Biological Species Human

Human ANGPT2 / Angiopoietin-2 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10691-G-F from Sino Biological Species Human Accession NM_001147.2

Human ANGPT2 / Angiopoietin-2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10691-G-N from Sino Biological Species Human Accession NM_001147.2

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10691-ACR from Sino Biological Species Human

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid - HG10691-UT from Sino Biological Species Human

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, N-His tag - HG10691-NH from Sino Biological Species Human

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10691-NF from Sino Biological Species Human

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10691-NM from Sino Biological Species Human

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10691-CY from Sino Biological Species Human

Human ANGPT2 / Angiopoietin-2 natural ORF mammalian expression plasmid, C-Flag tag - HG10691-CF from Sino Biological Species Human Accession NM_001147.2

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10691-CM from Sino Biological Species Human

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10691-NY from Sino Biological Species Human

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10691-ACG from Sino Biological Species Human

Human Angiopoietin-2/ANG2 Gene ORF cDNA clone expression plasmid, C-His tag - HG10691-CH from Sino Biological Species Human

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