Gene Symbol |
Ndufa4
|
Entrez Gene |
17992
|
Alt Symbol |
MLRQ
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
|
Other Description |
CI-MLRQ|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 (9 kDa, MLRQ)|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4|NADH-ubiquinone oxidoreductase MLRQ subunit|complex I-MLRQ|cytochrome c oxidase subunit NDUFA4
|
Swissprots |
Q9CQP6 Q62425
|
Accessions |
EDL13918 Q62425 AK005084 AK008357 BAB25627 AK008506 BAB25706 AK076036 BAC36137 AK154084 BC011114 AAH11114 U59509 AAB03395 NM_010886 NP_035016
|
Function |
Cytochrome c oxidase (COX, complex IV) is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. Required for complex IV maintenance (By similarity). {ECO:0000250}.
|
Subcellular Location |
Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|