Gene Symbol | Ndufa4 |
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Entrez Gene | 17992 |
Alt Symbol | MLRQ |
Species | Mouse |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 |
Other Description | CI-MLRQ|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 (9 kDa, MLRQ)|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4|NADH-ubiquinone oxidoreductase MLRQ subunit|complex I-MLRQ|cytochrome c oxidase subunit NDUFA4 |
Swissprots | Q9CQP6 Q62425 |
Accessions | EDL13918 Q62425 AK005084 AK008357 BAB25627 AK008506 BAB25706 AK076036 BAC36137 AK154084 BC011114 AAH11114 U59509 AAB03395 NM_010886 NP_035016 |
Function | Cytochrome c oxidase (COX, complex IV) is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. Required for complex IV maintenance (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFA4 CRISPR/Cas9 KO Plasmid (m) - sc-421843 from Santa Cruz Biotechnology
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NDUFA4 HDR Plasmid (m) - sc-421843-HDR from Santa Cruz Biotechnology
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NDUFA4 Double Nickase Plasmid (m) - sc-421843-NIC from Santa Cruz Biotechnology
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NDUFA4 Double Nickase Plasmid (m2) - sc-421843-NIC-2 from Santa Cruz Biotechnology
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NDUFA4 CRISPR Activation Plasmid (m) - sc-421843-ACT from Santa Cruz Biotechnology
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NDUFA4 CRISPR Activation Plasmid (m2) - sc-421843-ACT-2 from Santa Cruz Biotechnology
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NDUFA4 Lentiviral Activation Particles (m) - sc-421843-LAC from Santa Cruz Biotechnology
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NDUFA4 Lentiviral Activation Particles (m2) - sc-421843-LAC-2 from Santa Cruz Biotechnology
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NDUFA4 siRNA (m) - sc-106286 from Santa Cruz Biotechnology
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NDUFA4 shRNA Plasmid (m) - sc-106286-SH from Santa Cruz Biotechnology
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NDUFA4 shRNA (m) Lentiviral Particles - sc-106286-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN36293 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36293 from Sigma-Aldrich
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NDUFA4 siRNA (Mouse) - CRM2727 from Cohesion Biosciences
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shRNA set against Mouse NDUFA4 (NM_010886.2) - SHH350548 from Creative biogene
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shRNA set against Mouse Ndufa4(NM_010886.2) - SHR004640 from Creative biogene
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Mouse NDUFA4 siRNA - orb282203 from Biorbyt
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NDUFA4 shRNA Plasmid (Mouse) - CHM2727 from Cohesion Biosciences
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NDUFA4 miRNA 3'UTR clone - MiUTR1M-07556 from Creative biogene
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