COL12A1

Gene Symbol COL12A1
Entrez Gene 1303
Alt Symbol BA209D8.1, COL12A1L, DJ234P15.1
Species Human
Gene Type protein-coding
Description collagen, type XII, alpha 1
Other Description collagen alpha-1(XII) chain|collagen type XII proteoglycan
Swissprots Q5VYK2 Q71UR3 O43853 Q15955 Q99715 Q5VYK1 Q99716
Accessions AAC83578 EAW48748 EAW48749 EAW48750 Q99715 AI752603 AJ420501 AK057081 AK307558 BC034534 BC034715 BC050587 AAH50587 BC146868 AAI46869 BP286308 DA661773 U68139 AAC01506 U73778 AAC51244 U73779 AAD40483 XM_011535434 XP_011533736 XM_011535435 XP_011533737 XM_011535436 XP_011533738 NM_004370 NP_004361 NM_080645 NP_542376
Function Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix. {ECO:0000250}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity Found in collagen I-containing tissues: both isoform 1 and isoform 2 appear in amnion, chorion, skeletal muscle, small intestine, and in cell culture of dermal fibroblasts, keratinocytes and endothelial cells. Only isoform 2 is found in lung, placenta, kidney and a squamous cell carcinoma cell line. Isoform 1 is also present in the corneal epithelial Bowman's membrane (BM) and the interfibrillar matrix of the corneal stroma, but it is not detected in the limbal BM. {ECO:0000269|PubMed:9344363}.
Top Pathways Protein digestion and absorption

COL12A1 CRISPR/Cas9 KO Plasmid (h) - sc-402361 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

COL12A1 HDR Plasmid (h) - sc-402361-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COL12A1 Double Nickase Plasmid (h) - sc-402361-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COL12A1 Double Nickase Plasmid (h2) - sc-402361-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COL12A1 CRISPR Activation Plasmid (h) - sc-402361-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

COL12A1 CRISPR Activation Plasmid (h2) - sc-402361-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

COL12A1 Lentiviral Activation Particles (h) - sc-402361-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COL12A1 Lentiviral Activation Particles (h2) - sc-402361-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

COL12A1 siRNA (h) - sc-72958 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

COL12A1 shRNA Plasmid (h) - sc-72958-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

COL12A1 shRNA (h) Lentiviral Particles - sc-72958-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU066591 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6369 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6369 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11084 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11084

COL12A1 siRNA (Human) - CRH0917 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

COL12A1 - MBS8232673 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human COL12A1 (NM_004370.5) - SHH267041 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human COL12A1(NM_080645.2) - SHG189617 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human COL12A1(NM_004370.5) - SHG189653 from Creative biogene

Category siRNA
Species Reactivities Human

COL12A1 shRNA Plasmid (Human) - CHH0917 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

COL12A1 miRNA 3'UTR clone - MiUTR1H-02301 from Creative biogene

Species Reactivities Human

COL12A1 miRNA 3'UTR clone - MiUTR1H-02302 from Creative biogene

Species Reactivities Human
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