XRCC2

Gene Symbol XRCC2
Entrez Gene 7516
Alt Symbol -
Species Human
Gene Type protein-coding
Description X-ray repair complementing defective repair in Chinese hamster cells 2
Other Description DNA repair protein XRCC2|X-ray repair cross-complementing protein 2
Swissprots B2R925 O43543
Accessions AAC05802 AAM55241 CAA76597 EAW53967 EAW53968 O43543 AF035587 AAC05369 AK313607 BAG36372 BC042137 AAH42137 CR749256 CAH18112 Y08837 CAA70065 NM_005431 NP_005422
Function Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2- dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. {ECO:0000269|PubMed:11751635, ECO:0000269|PubMed:11834724, ECO:0000269|PubMed:21276791, ECO:0000269|PubMed:23149936}.
Subcellular Location Nucleus {ECO:0000269|PubMed:21276791}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:21276791}.
Top Pathways Homologous recombination

Human XRCC2 ELISA Kit (Sandwich ELISA) - LS-F9957 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 0.114 ng/ml
Range 0.313-20 ng/ml

X-ray repair complementing defective repair in Chinese hamster cells 2, ELISA Kit - MBS9340061 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for X-Ray Repair Cross Complementing 2 (XRCC2) - SEG147Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.114ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for X-Ray Repair Cross Complementing 2 (XRCC2) - SEG147Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.114ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human XRCC2 ELISA Kit - abx153524 from Abbexa

Category ELISA Kit
Sensitivity 0.114 ng/ml
Range 0.313 ng/ml - 20 ng/ml

Human XRCC2 ELISA Kit - E040720 from Biobool

Category ELISA Kit

XRCC2 ELISA Kit (Human) (OKCD01898) - OKCD01898 from Aviva Systems Biology

Category ELISA Kit
Prices $545.00
Sizes 96 wells
Sensitivity < 0.114 ng/mL
Range 0.312 - 20 ng/mL

anti-XRCC2 antibody - ARG53735 from Arigo Biolaboratories

Category ELISA Kit

anti-XRCC2 antibody (Ready-to-Use) - ARG53736 from Arigo Biolaboratories

Category ELISA Kit

Human DNA repair protein XRCC2 (XRCC2) ELISA Kit - AE10989HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
Sensitivity 0.114 ng/mL
Range 0.312-20 ng/mL
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