PDGFA

Gene Symbol	PDGFA
Entrez Gene	5154
Alt Symbol	PDGF-A, PDGF1
Species	Human
Gene Type	protein-coding
Description	platelet-derived growth factor alpha polypeptide
Other Description	PDGF A-chain|PDGF subunit A|PDGF-1|platelet-derived growth factor A chain|platelet-derived growth factor alpha chain|platelet-derived growth factor alpha isoform 2 preproprotein|platelet-derived growth factor subunit A
Swissprots	B5BU73 P04085
Accessions	AAA60045 AAA60046 AAA60047 AAB26566 AAD13863 AAD13864 AAK29998 AAN76486 CAA02288 CAA02293 CAA02624 CAB59509 CAH23423 CAJ32894 CAJ32906 CAL32765 CBH30541 EAW87160 EAW87161 EAW87162 P04085 A09204 CAA00830 AB451309 BAG70123 AB451439 BAG70253 AK292217 BAF84906 AU118732 BC109246 AAI09247 BC141593 AAI41594 BC146594 AAI46595 BE336646 BQ001096 BQ002008 X03795 CAA27421 X06374 CAA29677 XM_011515415 XP_011513717 XM_011515416 XP_011513718 XM_011515417 XP_011513719 XM_011515418 XP_011513720 XM_011515419 XP_011513721 NM_002607 NP_002598 NM_033023 NP_148983
Function	Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB (By similarity). {ECO:0000250}.
Subcellular Location	Secreted. Note=Released by platelets upon wounding.
Top Pathways	MicroRNAs in cancer, PI3K-Akt signaling pathway, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDGF AA Human ELISA Kit - ab100622 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 2.5 pg/ml Range 2.74 pg/ml - 2000 pg/ml

PDGF AB Human ELISA Kit - ab100623 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 10 pg/ml Range 10.24 pg/ml - 2500 pg/ml

Human PDGF-AA ELISA Kit (Sandwich ELISA) - LS-F5564 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.056 ng/ml Range 41.15-30000 pg/ml

Human PDGF-AA ELISA Kit (Sandwich ELISA) - LS-F6082 from LifeSpan Bioscience Category ELISA Kit Prices $480.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 41.15-30000 pg/ml

Rabbit PDGF-AA ELISA Kit (Sandwich ELISA) - LS-F5394 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 10.8 pg/ml Range 41.15-30000 pg/ml

Human PDGF-AA ELISA Kit (Sandwich ELISA) - LS-F471 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 41.15 pg/ml Range 41.15-30000 pg/ml

Rat PDGF-AA ELISA Kit (Sandwich ELISA) - LS-F519 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 93.75 pg/ml Range 41.15-30000 pg/ml

Mouse PDGF-AA ELISA Kit (Sandwich ELISA) - LS-F9673 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 32 pg/ml Range 41.15-30000 pg/ml

Human PDGF-AA ELISA Kit (Sandwich ELISA) - LS-F12285 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 41.15-30000 pg/ml

Mouse PDGF-AA ELISA Kit (Sandwich ELISA) - LS-F12286 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 78 Range 41.15-30000 pg/ml

HumanPDGF-AA ELISA Kit - RAB0394 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human PDGF-AA Luminex Performance Assay - LAN221 from R&D Systems

Human PDGF-AA Magnetic Luminex Performance Assay - LANM221 from R&D Systems

Human/Mouse PDGF-AA Quantikine ELISA Kit - DAA00B from R&D Systems Category ELISA Kit Prices $519.00 Sizes 1 kit Sensitivity 6.29 pg/mL Range 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Saliva)

Human PDGF-AA DuoSet ELISA - DY221 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

PDGF-AB ELISA Kit (Human) : 96 Wells (OKAG00240) - OKAG00240 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 16 pg/mL Range 16-1,000 pg/mL

Human PDGFA ELISA Kit - abx152674 from Abbexa Category ELISA Kit Sensitivity 0.063 ng/ml Range 0.156 ng/ml - 10 ng/ml

PDGF-AB, Human, ELISA Kit - BEK1186 from ARP American Research Products Category ELISA Kit Prices $479.00 Sizes 96 t Sensitivity < 3pg/ml Range 31.2 pg/ml-2000 pg/ml

Platelet Derived Growth Factor Subunit A, PDGFA, Human, ELISA Kit - E-EL-H1669 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Platelet Derived Growth Factor Subunit A (PDGFA), Human, ELISA Kit - SEA528Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.063ng/mL Range 0.156-10ng/mL

Platelet-derived growth factor subunit A, PDGFA, Human, ELISA Kit - E0112h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 31.2-2000 pg/mL

Platelet Derived Growth Factor Subunit A, PDGFA, Mouse, ELISA Kit - E-EL-M0923 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Platelet Derived Growth Factor Subunit A, PDGFA, Rat, ELISA Kit - E-EL-R0752 from ARP American Research Products Category ELISA Kit Prices $686.00 Sizes 96 t

Platelet Derived Growth Factor Subunit A, PDGFA, Rabbit, ELISA Kit - E-EL-RB1351 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Platelet Derived Growth Factor Subunit A, PDGFA, Chicken, ELISA Kit - E-EL-Ch1978 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

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