ACOT8

Gene Symbol	ACOT8
Entrez Gene	10005
Alt Symbol	HNAACTE, PTE-1, PTE-2, PTE1, PTE2, hACTE-III, hTE
Species	Human
Gene Type	protein-coding
Description	acyl-CoA thioesterase 8
Other Description	HIV-Nef associated acyl-CoA thioesterase|acyl-coenzyme A thioesterase 8|choloyl-CoA hydrolase|choloyl-coenzyme A thioesterase|long-chain fatty-acyl-CoA hydrolase|palmitoyl-CoA hydrolase|peroxisomal acyl-CoA thioesterase 1|peroxisomal acyl-coenzyme A thioester hydrolase 1|peroxisomal long-chain acyl-CoA thioesterase 1|thioesterase II|thioesterase III
Swissprots	O15261 O14734 Q17RX4
Accessions	EAW75794 EAW75795 EAW75796 EAW75797 EAW75798 O14734 AF014404 AAB71665 AF124264 AAD27616 AK056668 BAG51780 AK126206 AK292494 BAF85183 AK296973 BAG59516 AK298783 BAG60922 BC117155 AAI17156 BC117157 AAI17158 BI911038 BM986979 CR541771 CAG46570 CR541778 CAG46577 DB470803 HQ258192 ADR82946 X86032 CAA60024 XM_005260239 XP_005260296 XM_005260240 XP_005260297 XM_011528480 XP_011526782 XR_244130 NM_005469 NP_005460 NM_183385 NM_183386
Function	Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N- acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation. {ECO:0000250, ECO:0000269|PubMed:15194431}.
Subcellular Location	Peroxisome.
Tissue Specificity	Detected in a T-cell line (at protein level). Ubiquitous. {ECO:0000269|PubMed:9299485}.
Top Pathways	Primary bile acid biosynthesis, Peroxisome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Acyl-coenzyme A Thioesterase 8 full length protein - ab156739 from Abcam Category Protein Source E. coli Species Human

Human Acyl-coenzyme A Thioesterase 8 full length protein - ab160759 from Abcam Category Protein Source Wheat germ Species Human

Human Acyl-coenzyme A Thioesterase 8 protein fragment - ab160760 from Abcam Category Protein Source Wheat germ Species Human

ACOT8 Antibody Blocking Peptide - LS-E22662 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACOT8 Antibody Blocking Peptide - LS-E9966 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACOT8 Partial Recombinant Protein - H00010005-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ACOT8 Recombinant Protein - H00010005-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human ACOT8 Protein - NBP2-22676 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

ACOT8-Antibody-C-term-Blocking-Peptide - BP9144b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ACOT8 protein - orb191420 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source Escherichia Coli. Species Human

ACOT8 protein (His tag) - 80R-2820 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

ACOT8 (1-319, His-tag) - AR50939PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ACOT8 (1-319, His-tag) - AR50939PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ACOT8 - H00010005-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ACOT8 - H00010005-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ACOT8 - H00010005-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ACOT8 - H00010005-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ACOT8, 1-319aa, Human, His tag, E.coli - 01-P2115 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Recombinant Human ACOT8, His-tagged - ACOT8-7604H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human ACOT8, His-tagged - ACOT8-3141H from Creative Biomart Category Protein Source E. Coli or Yeast Species Human

ACOT8 Blocking Peptide - CBP3376 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

ACOT8 (P172) Peptide - BS3062P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Acyl-coenzyme A thioesterase 8(ACOT8) - CSB-YP001170HU CSB-EP001170HU CSB-BP001170HU CSB-MP001170HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ACOT8, 1-319aa, Human, His tag, E.coli - ATGP2115 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ACOT8 - MBS205417 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 100 µg, 500 µg Source E Coli Species Human

Search more