| Gene Symbol |
Ppp3r1
|
| Entrez Gene |
19058
|
| Alt Symbol |
CaNB1, Cnb1, MCIP1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
|
| Other Description |
PP2B beta 1|calcineurin subunit B type 1|protein phosphatase 2B regulatory subunit 1|protein phosphatase 3 regulatory subunit B alpha
|
| Swissprots |
Q63810 Q3V067 Q5F225
|
| Accessions |
EDL40683 Q63810 AK133403 BAE21637 AK145541 BAE26495 AK160423 AK160938 BAE36102 AK163241 BAE37251 BC002267 BY137249 S43864 AAB23171 NM_024459 NP_077779
|
| Function |
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:20639889}. Cell membrane {ECO:0000269|PubMed:20639889}. Cell membrane, sarcolemma {ECO:0000269|PubMed:20639889}. Note=Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocytes hypertrophy.
|
| Tissue Specificity |
Brain specific.
|
| Top Pathways |
Glucagon signaling pathway, Tuberculosis, Glutamatergic synapse, Amphetamine addiction, Oxytocin signaling pathway
|