Nampt

Gene Symbol	Nampt
Entrez Gene	59027
Alt Symbol	1110035O14Rik, AI314458, AI480535, NAmPRTase, Pbef, Pbef1, Visfatin
Species	Mouse
Gene Type	protein-coding
Description	nicotinamide phosphoribosyltransferase
Other Description	pre-B-cell colony-enhancing factor 1 homolog
Swissprots	Q99KQ4 Q8C3B5 Q9JKM0
Accessions	EDL36889 Q99KQ4 AF234625 AAF43208 AK004117 AK086415 BAC39664 AK153926 AK166270 BAE38671 AY679720 AAT72933 BC004059 AAH04059 BC018358 AAH18358 BY068469 CV561474 NM_021524 NP_067499
Function	The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma (By similarity). Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD- dependent SIRT1-mediated suppression. {ECO:0000250|UniProtKB:P43490, ECO:0000269|PubMed:12555668, ECO:0000269|PubMed:15381699, ECO:0000269|PubMed:19286518, ECO:0000269|PubMed:19299583}.
Subcellular Location	Nucleus {ECO:0000250|UniProtKB:P43490}. Cytoplasm {ECO:0000269|PubMed:12555668}. Secreted {ECO:0000250|UniProtKB:P43490}. Note=Under non-inflammatory conditions, visfatin predominantly exhibits a granular pattern within the nucleus. Secreted by endothelial cells upon IL-1beta stimulation. Abundantly secreted in milk, reaching 100-fold higher concentrations compared to maternal serum. {ECO:0000250|UniProtKB:P43490}.
Tissue Specificity	Ubiquitously expressed in lymphoid and non- lymphoid tissues. {ECO:0000269|PubMed:12555668}.
Top Pathways	Nicotinate and nicotinamide metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Nicotinamide phosphoribosyltransferase (NAMPT), Mouse, ELISA Kit - E03N0539 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Nicotinamide phosphoribosyltransferase, Nampt, Mouse, ELISA Kit - E0638m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Visfatin (VF), Mouse, ELISA Kit - SEA638Mu from ARP American Research Products Category ELISA Kit Prices $668.00 Sizes 96 t Sensitivity 13.2pg/mL Range 31.2-2,000pg/mL

Visfatin, Mouse, ELISA Kit - CSB-E08942m from ARP American Research Products Category ELISA Kit Prices $565.00, $835.00, $837.00, $839.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.08 ng/ml Range 0.31 ng/ml-20 ng/ml

Visfatin, Mouse, ELISA Kit - E03V0003 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 2.5-50ng/ml

Visfatin, Mouse, ELISA Kit - YHB1399Mo from ARP American Research Products Category ELISA Kit

Mouse Visfatin ELISA Kit - MV0046 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Visfatin, ELISA Kit - MBS022755 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Visfatin (VF), ELISA Kit - MBS266699 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Visfatin (VF), ELISA Kit - MBS2021605 from MyBioSource Category ELISA Kit Prices $350.00, $525.00, $715.00, $2,915.00, $5,315.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 13.4pg/mL. Range 31.25-2000pg/mL

Mouse Visfatin ELISA Kit - DEIA2154 from Creative Diagnostics Category ELISA Kit

Nampt/Visfatin (mouse/rat) ELISA Kit - DEIA5086 from Creative Diagnostics Category ELISA Kit

nicotinamide phosphoribosyltransferase, ELISA Kit - MBS703809 from MyBioSource Category ELISA Kit Prices $250.00, $575.00, $835.00, $3,040.00, $5,755.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Visfatin, ELISA Kit - MBS720646 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,850.00, $5,340.00 Sizes 48 -strip-wells- (Competitive), 96 -strip-wells- (Competitive), 5x96-strip-wells- (Competitive), 10x96-strip-wells- (Competitive)

Mouse visfatin ELISA Kit - CSB-E08942m from Cusabio Category ELISA Kit Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Mouse Visfatin ELISA - E03V0003 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

ELISA Kit for Visfatin (VF) - SEA638Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 13.4pg/mL. Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA's were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

Mouse Visfatin (VF) ELISA Kit - EKU08155 from Biomatik Category ELISA Kit Prices $680.00, $3,028.00, $5,511.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 13.4 pg/mL Range 31.25-2000 pg/mL

Mouse VF(Visfatin) ELISA Kit - E-EL-M1237 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.38 ng/mL Range 0.63~40 ng/mL

Mouse Visfatin ELISA Kit - abx254504 from Abbexa Category ELISA Kit Sensitivity 0.375 ng/ml Range 0.625 ng/ml - 40 ng/ml

Mouse Visfatin ELISA Kit - abx154855 from Abbexa Category ELISA Kit Sensitivity 13.2 pg/ml Range 31.25 pg/ml - 2000 pg/ml

Mouse Visfatin ELISA Kit - abx051490 from Abbexa Category ELISA Kit Sensitivity 1 pg/ml Range 5 pg/ml - 400 pg/ml

Visfatin (VF), Mouse, ELISA Kit - DL-VF-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 15.6-1,000 pg/mL

Mouse visfatin ELISA Kit - EKC38044 from Biomatik Category ELISA Kit Prices $840.00, $3,150.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Mouse Nicotinamide phosphoribosyltransferase ELISA Kit - EKE52958 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 0.312-20.00 ng/mL

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