NPSR1

Gene Symbol NPSR1
Entrez Gene 387129
Alt Symbol ASRT2, GPR154, GPRA, NPSR, PGR14, VRR1
Species Human
Gene Type protein-coding
Description neuropeptide S receptor 1
Other Description G-protein coupled receptor 154|G-protein coupled receptor PGR14|G-protein coupled receptor for asthma susceptibility|neuropeptide S receptor|vasopressin receptor-related receptor 1
Swissprots Q6JSL6 Q56H77 Q56H76 Q6W5P3 Q6JSL8 A2RTZ4 Q6ZMB8 Q6JSL4 Q6W5P4 Q2XP58 Q56H78 Q6JSL5 Q6JSL7
Accessions ABB72550 EAL24469 EAL24470 EAW94034 EAW94035 EAW94036 EAW94037 Q6W5P4 AK124929 AK172847 BAD18811 AY255536 AAO85048 AY310326 AAQ76966 AY310327 AAQ76967 AY310328 AAQ76968 AY310329 AAQ76969 AY310330 AAQ76970 AY310331 AAQ76971 AY310332 AAQ76972 AY956446 AAX63744 AY956447 AAX63745 AY956448 AAX63746 BC132693 AAI32694 BC132695 AAI32696 BC144380 AAI44381 HQ258213 ADR82967 NM_001300933 NP_001287862 NM_001300934 NP_001287863 NM_001300935 NP_001287864 NM_207172 NP_997055 NM_207173 NP_997056
Function G-protein coupled receptor for neuropeptide S (NPS) (PubMed:16790440). Promotes mobilization of intracellular Ca(2+) stores (PubMed:16790440). Inhibits cell growth in response to NPS binding (PubMed:15947423). Involved in pathogenesis of asthma and other IgE-mediated diseases. {ECO:0000269|PubMed:15312648, ECO:0000269|PubMed:15947423, ECO:0000269|PubMed:16790440}.
Subcellular Location Isoform 7: Cytoplasm {ECO:0000269|PubMed:15947423}.
Tissue Specificity Isoform 4 is ubiquitous; it is detected in glandular epithelia of bronchus, stomach, small intestine, colon, uterus, esophagus, spleen, kidney, pancreas, prostate and breast. Isoform 1 is detected in uterus, colon and prostate, and in the smooth muscle cell layer in bronchial and arterial walls (at protein level) (PubMed:15947423). Isoform 1 is predominantly expressed in smooth muscle. Isoform 4 is predominantly expressed in epithelial cells. In bronchial biopsies, it is expressed in smooth muscle cells of asthma patients, but not in control patients; whereas in epithelial cells, its expression is consistently stronger in asthma patients. {ECO:0000269|PubMed:15073379, ECO:0000269|PubMed:15947423}.

GPR154 CRISPR/Cas9 KO Plasmid (h) - sc-408608 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR154 HDR Plasmid (h) - sc-408608-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR154 Double Nickase Plasmid (h) - sc-408608-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR154 Double Nickase Plasmid (h2) - sc-408608-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR154 CRISPR Activation Plasmid (h) - sc-408608-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR154 CRISPR Activation Plasmid (h2) - sc-408608-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR154 Lentiviral Activation Particles (h) - sc-408608-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR154 Lentiviral Activation Particles (h2) - sc-408608-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR154 siRNA (h) - sc-89534 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR154 shRNA Plasmid (h) - sc-89534-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR154 shRNA (h) Lentiviral Particles - sc-89534-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR154 RNAi - H00387129-R04 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU096991 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU124611 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2585 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2585 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01918 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01918

NPSR1 siRNA (Human) - CRJ7729 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPR154 RNAi - H00387129-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NPSR1 (NM_207172.1) - SHH354456 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NPSR1(NM_207172.1) - SHR018894 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NPSR1(NM_207173.1) - SHR018912 from Creative biogene

Category siRNA
Species Reactivities Human

Human NPSR1 siRNA - orb278230 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NPSR1 shRNA Plasmid (Human) - CHJ7729 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NPSR1 miRNA 3'UTR clone - MiUTR1H-06883 from Creative biogene

Species Reactivities Human
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