Gene Symbol |
SERPINA10
|
Entrez Gene |
51156
|
Alt Symbol |
PZI, ZPI
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
|
Other Description |
PZ-dependent protease inhibitor|protein Z-dependent protease inhibitor|serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10|serpin A10
|
Swissprots |
Q86U20 Q6UWX9 Q9UK55 A5Z2A5
|
Accessions |
ABR09269 EAW81564 EAW81565 EAW81566 Q9UK55 AF181467 AAD53962 AI174900 AK314877 BAG37392 AY358597 AAQ88960 BC022261 AAH22261 BX248011 CAD62339 DQ891997 ABM82923 DQ895187 ABM86113 XM_005267733 XP_005267790 XM_006720159 XP_006720222 XM_006725163 XP_006725226 XM_006725164 XP_006725227 NM_001100607 NP_001094077 NM_016186 NP_057270
|
Function |
Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors. {ECO:0000269|PubMed:11049983}.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Expressed by the liver and secreted in plasma.
|