Gene Symbol | SERPINA10 |
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Entrez Gene | 51156 |
Alt Symbol | PZI, ZPI |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
Other Description | PZ-dependent protease inhibitor|protein Z-dependent protease inhibitor|serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10|serpin A10 |
Swissprots | Q86U20 Q6UWX9 Q9UK55 A5Z2A5 |
Accessions | ABR09269 EAW81564 EAW81565 EAW81566 Q9UK55 AF181467 AAD53962 AI174900 AK314877 BAG37392 AY358597 AAQ88960 BC022261 AAH22261 BX248011 CAD62339 DQ891997 ABM82923 DQ895187 ABM86113 XM_005267733 XP_005267790 XM_006720159 XP_006720222 XM_006725163 XP_006725226 XM_006725164 XP_006725227 NM_001100607 NP_001094077 NM_016186 NP_057270 |
Function | Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors. {ECO:0000269|PubMed:11049983}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
ZPI CRISPR/Cas9 KO Plasmid (h) - sc-412134 from Santa Cruz Biotechnology
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ZPI HDR Plasmid (h) - sc-412134-HDR from Santa Cruz Biotechnology
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ZPI Double Nickase Plasmid (h) - sc-412134-NIC from Santa Cruz Biotechnology
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ZPI Double Nickase Plasmid (h2) - sc-412134-NIC-2 from Santa Cruz Biotechnology
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ZPI CRISPR Activation Plasmid (h) - sc-412134-ACT from Santa Cruz Biotechnology
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ZPI CRISPR Activation Plasmid (h2) - sc-412134-ACT-2 from Santa Cruz Biotechnology
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ZPI Lentiviral Activation Particles (h) - sc-412134-LAC from Santa Cruz Biotechnology
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ZPI Lentiviral Activation Particles (h2) - sc-412134-LAC-2 from Santa Cruz Biotechnology
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ZPI siRNA (h) - sc-63257 from Santa Cruz Biotechnology
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ZPI shRNA Plasmid (h) - sc-63257-SH from Santa Cruz Biotechnology
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ZPI shRNA (h) Lentiviral Particles - sc-63257-V from Santa Cruz Biotechnology
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Serpin A10/ZPI RNAi - H00051156-R01 from Novus Biologicals
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Serpin A10/ZPI RNAi - H00051156-R02 from Novus Biologicals
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MISSION® esiRNA - EHU040611 from Sigma-Aldrich
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MISSION® esiRNA - EHU111041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1905 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1905 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05552 from Sigma-Aldrich
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SERPINA10 siRNA (Human) - CRH9569 from Cohesion Biosciences
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SERPINA10 - MBS8201899 from MyBioSource
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shRNA set against Human SERPINA10 (NM_016186.2) - SHH404892 from Creative biogene
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shRNA set against Human SERPINA10(NM_016186.2) - SHR216580 from Creative biogene
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Human SERPINA10 siRNA - orb270071 from Biorbyt
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SERPINA10 shRNA Plasmid (Human) - CHH9569 from Cohesion Biosciences
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SERPINA10 miRNA 3'UTR clone - MiUTR1H-09291 from Creative biogene
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