Gene Symbol | TPK1 |
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Entrez Gene | 27010 |
Alt Symbol | HTPK1, PP20, THMD5 |
Species | Human |
Gene Type | protein-coding |
Description | thiamin pyrophosphokinase 1 |
Other Description | placental protein 20|thiamine diphosphokinase|thiamine kinase |
Swissprots | Q9H602 I6L9B8 A8K0T7 Q6NUR5 Q9H3S4 D3DWG0 |
Accessions | AAS00370 EAL24415 EAW80091 EAW80092 Q9H3S4 AB028138 BAB20326 AF297710 AAK01351 AK021810 AK026374 BAB15465 AK091736 BAG52408 AK128661 BAC87556 AK130640 AK289652 BAF82341 AK308693 AY206415 AAO38775 BC014552 BC040555 AAH40555 BC068460 AAH68460 BI770816 BX446289 CR749248 CAH18104 DA135998 XM_005249970 XP_005250027 XM_006715925 XP_006715988 XM_011516031 XP_011514333 XM_011516032 XP_011514334 XM_011516033 XP_011514335 XM_011516034 XP_011514336 XM_011516035 XP_011514337 XM_011516036 XP_011514338 XM_011516037 XP_011514339 XM_011516038 XP_011514340 XM_011516039 XP_011514341 XM_011516040 XP_011514342 XM_011516041 XP_011514343 XM_011516042 XP_011514344 XM_011516043 XP_011514345 XM_011516044 XP_011514346 XM_011516045 XP_011514347 XM_011516046 XP_011514348 XM_011516047 XP_011514349 XM_011516048 XP_011514350 XM_011516049 XP_011514351 XM_011516050 XP_011514352 XR_927446 XR_927448 XR_927450 XR_927451 XR_927453 NM_001042482 NP_001035947 NM_022445 NP_071890 |
Function | Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate. {ECO:0000269|PubMed:11342111}. |
Tissue Specificity | Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues. {ECO:0000269|PubMed:11342111, ECO:0000269|PubMed:11342117}. |
Top Pathways | Thiamine metabolism |
Human TPK1 full length protein - ab123150 from Abcam
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Human TPK1 full length protein - ab200487 from Abcam
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TPK1 Antibody Blocking Peptide - LS-E9965 from LifeSpan Bioscience
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TPK1 Antibody Blocking Peptide - LS-E20008 from LifeSpan Bioscience
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TPK1 Partial Recombinant Protein - H00027010-Q01 from Novus Biologicals
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TPK1 Recombinant Protein - H00027010-P01 from Novus Biologicals
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Recombinant Human TPK1 Protein - NBP1-99102 from Novus Biologicals
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TPK1-Antibody-N-term-Blocking-Peptide - BP9142a from Abgent, a WuXi AppTec company
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Human TPK1 protein - orb169464 from Biorbyt
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TPK1 Blocking Peptide - 33R-9983 from Fitzgerald
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TPK1 protein (His tag) - 80R-2159 from Fitzgerald
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Thiamine pyrophosphokinase 1 (TPK1) (1-243, His-tag) - AR50240PU-N from Acris Antibodies
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Thiamine pyrophosphokinase 1 (TPK1) (1-243, His-tag) - AR50240PU-S from Acris Antibodies
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Thiamine pyrophosphokinase 1 (TPK1) - H00027010-P01-10 from Acris Antibodies
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Thiamine pyrophosphokinase 1 (TPK1) - H00027010-P01-25 from Acris Antibodies
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Thiamine pyrophosphokinase 1 (TPK1) - H00027010-Q01 from Acris Antibodies
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Thiamine pyrophosphokinase 1 (TPK1) - H00027010-Q01-10 from Acris Antibodies
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Thiamine pyrophosphokinase 1 (TPK1) - H00027010-Q01-25 from Acris Antibodies
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TPK1, 1-243aa, Human, His tag, E.coli - 01-P1415 from ARP American Research Products
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TPK1 Recombinant Protein - 96-742 from ProSci
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TPK1 fusion protein - Ag1404 from Proteintech Group
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TPK1 Human - PKPS-030 from NeoScientific
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Recombinant Human Thiamin Pyrophosphokinase 1 Enzyme - BP002761-PKA-023 from Syd Labs
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Recombinant Human Thiamin Pyrophosphokinase 1, His-tagged - TPK1-1937H from Creative Biomart
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Recombinant Human TPK1, GST-tagged - TPK1-3369H from Creative Biomart
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