Gene Symbol | EHD1 |
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Entrez Gene | 10938 |
Alt Symbol | H-PAST, HPAST1, PAST, PAST1 |
Species | Human |
Gene Type | protein-coding |
Description | EH-domain containing 1 |
Other Description | EH domain-containing protein 1|PAST homolog 1|testilin |
Swissprots | Q9UNR3 Q2M3Q4 O14611 Q9H4M9 |
Accessions | CAF06408 EAW74317 EAW74318 EAW74319 EAW74320 EAW74321 Q9H4M9 AF001434 AAB81204 AF099011 AAD45866 AK096747 AK097842 BAG53542 AK098723 AK124613 AK126581 AK297654 BAG60021 AK299096 BAG61156 AK300326 BAG62076 AK302930 BAG64091 AK312316 BAG35240 AY007161 AAG02009 BC036898 BC104799 AAI04800 BC104825 AAI04826 BM677440 DB093699 DC397966 DC399803 XM_011544739 XP_011543041 NM_001282444 NP_001269373 NM_001282445 NP_001269374 NM_006795 NP_006786 |
Function | Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Plays a role in myoblast fusion. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. {ECO:0000269|PubMed:15020713, ECO:0000269|PubMed:17233914, ECO:0000269|PubMed:20801876}. |
Subcellular Location | Recycling endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Preferentially associates with tubular recycling endosomes. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes. |
Tissue Specificity | Highly expressed in testis. |
Top Pathways | Endocytosis |
EHD (E-5) - sc-271658 from Santa Cruz Biotechnology
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EHD (D-12) - sc-390584 from Santa Cruz Biotechnology
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EHD (E-8) - sc-390513 from Santa Cruz Biotechnology
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EHD (F-11) - sc-390514 from Santa Cruz Biotechnology
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EHD (H-210) - sc-32917 from Santa Cruz Biotechnology
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EHD (L-19) - sc-23452 from Santa Cruz Biotechnology
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EHD (A-20) - sc-23450 from Santa Cruz Biotechnology
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Anti-EHD1 antibody - ab75886 from Abcam
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Anti-EHD1 antibody - ab118557 from Abcam
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Anti-EHD1 antibody [EPR4954] - ab109311 from Abcam
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Anti-EHD1 antibody [EPR4955] - ab109747 from Abcam
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Anti-Testilin / EHD1 Antibody (Internal, clone EPR4954) - LS-C138267 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (Internal, clone EPR4955) IHC-plus™ - LS-B7694 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (C-Terminus) - LS-C116466 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa409-438, AP) - LS-C256527 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa409-438, APC) - LS-C256530 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa409-438, Biotin) - LS-C256531 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa409-438, FITC) - LS-C256532 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa409-438, PE) - LS-C256534 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa409-438, Azide-free, HRP) - LS-C256533 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa409-438) - LS-C321045 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (C-Terminus) - LS-C345500 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa409-438) - LS-C167667 from LifeSpan Bioscience
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Anti-Testilin / EHD1 Antibody (aa2-15) IHC-plus™ - LS-B5111 from LifeSpan Bioscience
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EHD1 Antibody (EPR4954) - NBP1-95580 from Novus Biologicals
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