ATXN1

Gene Symbol ATXN1
Entrez Gene 6310
Alt Symbol ATX1, D6S504E, SCA1
Species Human
Gene Type protein-coding
Description ataxin 1
Other Description alternative ataxin1|ataxin-1|spinocerebellar ataxia type 1 protein
Swissprots Q9UJG2 Q9Y4J1 Q17S02 P54253
Accessions AAD14401 EAW55370 EAW55371 EAW55372 EAW55373 EAW55374 P54253 AA774255 AK311274 AK311649 BC010948 BC011026 AAH11026 BC014548 AAH14548 BC029401 BC039236 BC047894 BC063120 BC092446 BC113082 BC117125 AAI17126 BF666802 BF670717 BP365416 BX505133 HQ258517 ADR83271 JX901140 AGA61747 N52856 X79204 CAA55793 NM_000332 NP_000323 NM_001128164 NP_001121636
Function Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function. {ECO:0000269|PubMed:21475249}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:12093161}. Note=Colocalizes with USP7 in the nucleus.
Tissue Specificity Widely expressed throughout the body.

Ataxin-1 CRISPR/Cas9 KO Plasmid (h) - sc-403309 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-1 HDR Plasmid (h) - sc-403309-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-1 Double Nickase Plasmid (h) - sc-403309-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-1 Double Nickase Plasmid (h2) - sc-403309-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-1 CRISPR Activation Plasmid (h) - sc-403309-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-1 CRISPR Activation Plasmid (h2) - sc-403309-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-1 Lentiviral Activation Particles (h) - sc-403309-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-1 Lentiviral Activation Particles (h2) - sc-403309-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ataxin-1 siRNA (h) - sc-43624 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin-1 shRNA Plasmid (h) - sc-43624-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin-1 shRNA (h) Lentiviral Particles - sc-43624-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ataxin 1 RNAi - H00006310-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU096281 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN3757 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3757 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ATXN1 siRNA (Human) - CRH4252 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATXN1 - MBS8222944 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Atxn1 (NM_000332.3) - SHH243522 from Creative biogene

Category siRNA
Species Reactivities Human

Human ATXN1 siRNA - orb264754 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATXN1 shRNA Plasmid (Human) - CHH4252 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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