ATXN1

Gene Symbol ATXN1
Entrez Gene 6310
Alt Symbol ATX1, D6S504E, SCA1
Species Human
Gene Type protein-coding
Description ataxin 1
Other Description alternative ataxin1|ataxin-1|spinocerebellar ataxia type 1 protein
Swissprots Q9UJG2 Q9Y4J1 Q17S02 P54253
Accessions AAD14401 EAW55370 EAW55371 EAW55372 EAW55373 EAW55374 P54253 AA774255 AK311274 AK311649 BC010948 BC011026 AAH11026 BC014548 AAH14548 BC029401 BC039236 BC047894 BC063120 BC092446 BC113082 BC117125 AAI17126 BF666802 BF670717 BP365416 BX505133 HQ258517 ADR83271 JX901140 AGA61747 N52856 X79204 CAA55793 NM_000332 NP_000323 NM_001128164 NP_001121636
Function Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function. {ECO:0000269|PubMed:21475249}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000269|PubMed:12093161}. Note=Colocalizes with USP7 in the nucleus.
Tissue Specificity Widely expressed throughout the body.

Ataxin-1 Antibody - 2177 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from rat and mouse brain using Ataxin-1 Antibody.

Ataxin-1 (H-21) - sc-12527 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ataxin-1 (H-21): sc-12527. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells.

Ataxin-1 (H-175) - sc-366868 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ataxin-1 (H-175): sc-366868. Western blot analysis of Ataxin-1 expression in non-transfected: sc-117752 (A) and mouse Ataxin-1 transfected: sc-118599 (B) 293T whole cell lysates.

Ataxin-1 (L-19) - sc-12526 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ataxin-1 (L-19): sc-12526. Western blot analysis of Ataxin-1 expression in non-transfected: sc-117752 (A) and mouse Ataxin-1 transfected: sc-118599 (B) 293T whole cell lysates.

Ataxin-1 (C-20) - sc-8766 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Ataxin-1 (C-20): sc-8766. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells.

Anti-Ataxin 1 (phospho S775) antibody - ab182638 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ataxin 1 (phospho S775) antibody (ab182638) at 1/500 dilutionLane 1 : HepG2 cell lysate with immunizing peptideLane 2 : HepG2 cell lysate

Anti-Ataxin 1 (phospho S775) antibody - ab192217 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ataxin 1 (phospho S775) antibody (ab192217) at 1/500 dilutionLane 1 : Adriamycin treated HepG2 whole cell lysates with Antigen-specific peptideLane 2 : Adriamycin treated HepG2 whole cell lysatesLysates/proteins at 12.5 µg per lane.

Anti-Ataxin 1 (phospho S776) antibody - ab63376 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ataxin 1 (phospho S776) antibody (ab63376) at 1/500 dilutionLane 1 : HepG2 cell extract treated with Adriamycin (0.5 micromoles, 5hours)Lane 2 : HepG2 cell extract treated with Adriamycin (0.5 micromoles, 5hours) with immunizing phosphopeptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Ataxin 1 antibody - ab111401 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-Ataxin 1 antibody - ab110833 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab110833 at 1/50 staining Ataxin 1 in paraffin-embedded Human lung carcinoma tissue, left panel shows staining without immunizing peptide right panel shows staining with immunizing peptide.

Anti-Ataxin 1 antibody - ab118137 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-Ataxin 1 antibody - ab114045 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of Ataxin 1 in Immunoprecipitates of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab114045 at 10 µg/mg lysate for IP. An anti-Ataxin 1 antibody which recognizes a downstream epitope was used at 1 µg/ml for subsequent western blot detection. Detection: Chemiluminescence with exposure time of 3 seconds.

Anti-Ataxin 1 antibody [2F5] - ab107256 from Abcam

Host Mouse
Clonality Monoclonal
Clone 2F5
All lanes : Anti-Ataxin 1 antibody [2F5] (ab107256) at 1/500 dilutionLane 1 : HEK293Lane 2 : HEK293 transfected with Ataxin 1-hIgGFc

Anti-Ataxin 1 antibody [S65-37] - ab186393 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S65-37

Anti-Ataxin 1 antibody [S65-37] (Biotin) - ab186353 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S65-37

Anti-Ataxin 1 antibody [S65-37] (FITC) - ab186367 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S65-37

Anti-Ataxin 1 antibody [S65-37] - C-terminal (HRP) - ab186345 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S65-37

Anti-Ataxin 1 antibody [S76-8] (FITC) - ab186249 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S76-8

Anti-Ataxin 1 antibody [S768] - ab186265 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S768

Anti-Ataxin 1 antibody [S768] (Biotin) - ab186327 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S768

Anti-Ataxin 1 antibody [S768] (HRP) - ab186308 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S768

Anti-Ataxin 1 antibody - C-terminal - ab187117 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Ataxin 1 antibody - C-terminal (ab187117) at 1/1000 dilution + Mouse thymus total cell extract

Anti-ATXN1 / SCA1 Antibody - LS-C92171 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ATXN1 / SCA1 Antibody (Internal) - LS-C112868 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ATXN1 / SCA1 Antibody - LS-C122704 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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