BCL11A

Gene Symbol BCL11A
Entrez Gene 53335
Alt Symbol BCL11A-L, BCL11A-S, BCL11A-XL, BCL11a-M, CTIP1, EVI9, HBFQTL5, ZNF856
Species Human
Gene Type protein-coding
Description B-cell CLL/lymphoma 11A (zinc finger protein)
Other Description B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2|B-cell lymphoma/leukemia 11A|BCL-11A|BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1|C2H2-type zinc finger protein|COUP-TF-interacting protein 1|EVI-9|ecotropic viral integration site 9 homolog|ecotropic viral integration site 9 protein homolog|zinc finger protein 856
Swissprots Q9H163 Q8WU92 Q9NWA7 D6W5D7 Q9H164 Q9H165 Q86W14 Q96JL6 Q9H3G9
Accessions AAX93205 AAY14784 ADL14507 ADL14508 EAX00035 EAX00036 EAX00037 EAX00038 EAX00039 EAX00040 EAX00041 Q9H165 AB058712 BAB47438 AF080216 AAG49025 AJ404611 CAC17723 AJ404612 CAC17724 AJ404613 CAC17725 AK001035 AK055251 BAG51490 AK092316 BAG52530 AK297507 BAG59920 AK300012 BAG61828 AY228763 AAO88272 AY692278 AAU04557 BC021098 AAH21098 BG393787 EU446622 ABZ92151 EU446808 ABZ92337 JN852960 AEV45616 XM_011532909 XP_011531211 XM_011532910 XP_011531212 XM_011532911 XP_011531213 XM_011532912 XP_011531214 XM_011532913 XP_011531215 XM_011532914 XP_011531216 XM_011532915 XP_011531217 NM_018014 NP_060484 NM_022893 NP_075044 NM_138559 NP_612569 NM_138553
Function Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11161790}. Nucleus {ECO:0000269|PubMed:11161790}. Note=Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles (By similarity). {ECO:0000250}.
Tissue Specificity Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development. {ECO:0000269|PubMed:11161790, ECO:0000269|PubMed:11719382}.

Bcl-11a CRISPR/Cas9 KO Plasmid (h) - sc-403612 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bcl-11a HDR Plasmid (h) - sc-403612-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bcl-11a Double Nickase Plasmid (h) - sc-403612-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bcl-11a Double Nickase Plasmid (h2) - sc-403612-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bcl-11a CRISPR Activation Plasmid (h) - sc-403612-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bcl-11a CRISPR Activation Plasmid (h2) - sc-403612-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bcl-11a Lentiviral Activation Particles (h) - sc-403612-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bcl-11a Lentiviral Activation Particles (h2) - sc-403612-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bcl-11a siRNA (h) - sc-43578 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Bcl-11a shRNA Plasmid (h) - sc-43578-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Bcl-11a shRNA (h) Lentiviral Particles - sc-43578-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ctip1 RNAi - H00053335-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Ctip1 RNAi - H00053335-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU145981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1501 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1502 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1502 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BCL11A siRNA (Human) - CRH9956 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Ctip1 RNAi - H00053335-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Ctip1 RNAi - H00053335-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

BCL11A - MBS8217183 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BCL11A (NM_018014.3) - SHH245858 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BCL11A(NM_138559.1) - SHG096981 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BCL11A(NM_022893.3) - SHG097017 from Creative biogene

Category siRNA
Species Reactivities Human
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