HHEX

Gene Symbol HHEX
Entrez Gene 3087
Alt Symbol HEX, HMPH, HOX11L-PEN, PRH, PRHX
Species Human
Gene Type protein-coding
Description hematopoietically expressed homeobox
Other Description hematopoietically-expressed homeobox protein HHEX|homeobox protein HEX|homeobox protein PRH|homeobox, hematopoietically expressed|proline-rich homeodomain-containing transcription factor
Swissprots B1AQ17 Q03014 Q96CE9
Accessions AAK12833 EAW50087 EAW50088 Q03014 AA810064 AK309463 AK314891 BAG37405 BC014336 AAH14336 BC015110 AAH15110 BC050638 AAH50638 BI823658 BM543214 DB504532 EU446478 ABZ92007 L16499 AAA02988 X67235 CAA47661 Z21533 CAA79730 NM_002729 NP_002720
Function Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Liver and promyelocytic leukemia cell line HL- 60. {ECO:0000269|PubMed:1360645, ECO:0000269|PubMed:8096636, ECO:0000269|PubMed:8103988}.
Top Pathways Maturity onset diabetes of the young, Transcriptional misregulation in cancer

Hex (H-180) - sc-366054 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Hex (H-180): sc-366054. Western blot analysis of Hex expression in MCF7 (A) and HT-29 (B) whole cell lysates.

Hex (L-19) - sc-15128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Hex (P-21) - sc-15129 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Hex (P-21): sc-15129. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bone marrow tissue showing nuclear and cytoplasmic staining of hematopoietic cells.

Hex (HHE5I261) - sc-81284 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Hex (HHE5I261): sc-81284 Western Blot analysis of human recombinant Hex fusion protein.

Anti-Hex antibody - ab95438 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Hex antibody (ab95438) at 1 µg/mlLane 1 : Lysate prepared from rat liver tissue.Lane 2 : Lysate prepared from rat thymus tissue.Lane 3 : Lysate prepared from rat lung tissue.Lane 4 : Lysate prepared from rat pancreas tissue.Lane 5 : Whole cell lysate prepared from HT1080 cells.Lane 6 : Whole cell lysate prepared from MM453 cells.Lane 7 : Whole cell lysate prepared from SMMC cells.Lane 8 : Whole cell lysate prepared from 6T-CEM cells.Lane 9 : Whole cell lysate prepared from Colo320 cells.

Anti-Hex antibody [3E6] - ab117864 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E6
All lanes : Anti-Hex antibody [3E6] (ab117864) at 1/1000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY controlLane 2 : HEK293T cells transfected with pCMV6-ENTRY Hex cDNALysates/proteins at 5 µg per lane.

Anti-Hex antibody [EPR3361] - ab79392 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3361
All lanes : Anti-Hex antibody [EPR3361] (ab79392) at 1/2000 dilution (unpurified)Lane 1 : MCF7 cell lysateLane 2 : A549 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP-conjugated goat anti-rabbit IgG at 1/2000 dilution

Anti-Hex antibody [HHE5I261] - ab50836 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HHE5I261
Anti-Hex antibody [HHE5I261] (ab50836)Observed band size : 43 kDa (why is the actual band size different from the predicted?)

Anti-Hex antibody - ChIP Grade - ab34222 from Abcam

Prices $387.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Hex antibody - ChIP Grade (ab34222) at 1 µg/ml + Liver (Mouse) Tissue Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutionPerformed under reducing conditions.

HHEX Antibody (1A5) - H00003087-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A5
Western Blot: HHEX Antibody (1A5) [H00003087-M02] - HHEX monoclonal antibody (M02), clone 1A5. Analysis of HHEX expression in human placenta.

HHEX Antibody (3E6) - NBP1-47792 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E6

HHEX Antibody - H00003087-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

HHEX Antibody - NBP2-16811 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HHEX Antibody - H00003087-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Hex Antibody [H00003087-B01] - analysis of HHEX expression in transfected 293T cell line by HHEX MaxPab polyclonal antibody (B01). Lane 1: HHEX transfected lysate (30.00 KDa). Lane 2: Non-transfected lysate.

HHEX Antibody (1A2) - H00003087-M03 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A2
ELISA: Hex Antibody (1A2) [H00003087-M03] - Detection limit for recombinant GST tagged HHEX is approximately 0.1ng/ml as a capture antibody.

HHEX Antibody (2C8) - H00003087-M12 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C8
Western Blot: HHEX Antibody (2C8) [H00003087-M12] - Analysis of HHEX expression in LNCaP (Cat # L004V1).

HHEX Antibody (3H6) - H00003087-M05 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H6
ELISA: Hex Antibody (3H6) [H00003087-M05] - Detection limit for recombinant GST tagged HHEX is approximately 0.1ng/ml as a capture antibody.

HHEX Antibody (4E9) - H00003087-M10 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E9
Western Blot: Hex Antibody (4E9) [H00003087-M10] - EX monoclonal antibody (M10), clone 4E9 Western Blot analysis of HHEX expression in K-562 ( Cat # L009V1 ).

HHEX Antibody (4E2) - H00003087-M06 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E2
ELISA: Hex Antibody (4E2) [H00003087-M06] - Detection limit for recombinant GST tagged HHEX is approximately 0.1ng/ml as a capture antibody.

HHEX Antibody - H00003087-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Hex Antibody [H00003087-D01P] - analysis of HHEX expression in transfected 293T cell line by HHEX MaxPab rabbit polyclonal antibody. Lane 1: HHEX transfected lysate (30.00 KDa). Lane 2: Non-transfected lysate.

HHEX Antibody (3F11) - H00003087-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3F11
Western Blot: Hex Antibody (3F11) [H00003087-M01] - EX monoclonal antibody (M01), clone 3F11. Western Blot analysis of HHEX expression in human placenta. (~40kD,Pediatric Research 48:634-638,2000,http://www.pedresearch.org/cgi/content/full/48/5/634)

HHEX Antibody (2B12) - H00003087-M13 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B12

HHEX Polyclonal Antibody - bs-6600R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HHEX antibody produced in rabbit - HPA051894 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HHEX: <B>Cat. No. HPA051894</B>: Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells.

Monoclonal Anti-HHEX antibody produced in mouse - SAB1403914 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A5
<B>Immunofluorescence</B><BR/>Monoclonal Anti-HHEX: <B>Cat. No. SAB1403914</B>: Antibody concentration: 10 μg/mL using HeLa cell.
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