PCSK7

Gene Symbol PCSK7
Entrez Gene 9159
Alt Symbol LPC, PC7, PC8, SPC7
Species Human
Gene Type protein-coding
Description proprotein convertase subtilisin/kexin type 7
Other Description lymphoma proprotein convertase|prohormone convertase 7|prohormone convertase PC7|proprotein convertase 7|proprotein convertase 8|proprotein convertase PC7|subtilisin/kexin-like protease PC7
Swissprots Q96FK8 Q3C1X1 Q53GM4 B0YJ60 Q9UL57 Q16549
Accessions AAD55137 ACA06036 EAW67303 EAW67304 EAW67305 Q16549 AB231710 BAE46876 AB231711 AB231712 AK027156 AK097207 BAG53434 AK127262 AK222907 BAD96627 AK312429 BAG35338 BC006357 AAH06357 BC010696 AAH10696 BT006870 AAP35516 DA126121 DQ890632 ABM92249 DQ893803 ABM84729 EL950661 U33849 AAB03087 U40623 AAC50417 XM_006718939 XP_006719002 XM_006718940 XP_006719003 XM_011543061 XP_011541363 XM_011543062 XP_011541364 XR_428984 XR_947870 XR_947871 NM_004716 NP_004707
Function Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif.
Subcellular Location Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Seems to be localized intracellularly to the trans Golgi network. {ECO:0000250}.
Tissue Specificity Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte.

PC7/8 (H-73) - sc-366634 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

PC7/8 (V-20) - sc-22903 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PC7/8 (V-20): sc-22903. Western blot analysis of PC7/8 expression in Jurkat whole cell lysate.

Anti-PCSK7 antibody - ab47925 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PCSK7 antibody (ab47925) at 1/1000 dilutionLane 1 : Tissue lysate prepared from mouse prostate at 20 µlLane 2 : Tissue lysate prepared from mouse prostate at 10 µl

Anti-PCSK7 antibody - ab168593 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PCSK7 antibody (ab168593) at 1 µg/mlLane 1 : PCSK7-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-PCSK7 antibody - ab47926 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PCSK7 antibody (ab47926) at 1/1000 dilutionLane 1 : rH-PC-7 at 0.04 µgLane 2 : rH-PC-7 at 0.02 µgLane 3 : rH-PC-7 at 0.01 µg

Anti-PCSK7 antibody - ab116567 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PCSK7 antibody (ab116567) at 1/100 dilution + K562 cell line lysate at 35 µg

Anti-PCSK7 antibody - ab40134 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PCSK7 antibody - Aminoterminal end - ab39874 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PCSK7 antibody - Aminoterminal end (ab39874) at 1/1000 dilutionLane 1 : Recombinant human PC7 at 0.05 µgLane 2 : Recombinant human PC7 at 0.01 µgLane 3 : Recombinant human PC7 at 0.001 µg

Anti-PCSK7 / PC7 Antibody (aa692-721, AP) - LS-C223610 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCSK7 / PC7 Antibody (aa692-721, APC) - LS-C223611 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCSK7 / PC7 Antibody (aa692-721, Biotin) - LS-C223612 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCSK7 / PC7 Antibody (aa692-721, FITC) - LS-C223613 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCSK7 / PC7 Antibody (aa692-721, PE) - LS-C223614 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCSK7 / PC7 Antibody (aa692-721, Azide-free, HRP) - LS-C223615 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCSK7 / PC7 Antibody (aa691-721) - LS-C323866 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PCSK7 / PC7 Antibody (aa692-721) - LS-C163451 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PCSK7 Antibody western blot of K562 cell line lysates (35 ug/lane). The PCSK7 antibody detected the PCSK7 protein (arrow).

Proprotein Convertase 7/PCSK7 Antibody - NBP1-81292 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCSK7 Antibody [NBP1-81292] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401489)

Proprotein Convertase 7/PCSK7 Antibody (1B8) - NBP2-02106 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B8
Immunocytochemistry/Immunofluorescence: PCSK7 Antibody (1B8) [NBP2-02106] Staining of COS7 cells transiently transfected by pCMV6-ENTRY PCSK7.

Proprotein Convertase 7/PCSK7 Antibody - H00009159-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Proprotein Convertase 7/PCSK7 Antibody - H00009159-B01 from Novus Biologicals

Host Mouse
Clonality Polyclonal
Western Blot: PCSK7 Antibody [H00009159-B01] - analysis of PCSK7 expression in transfected 293T cell line by PCSK7 MaxPab polyclonal antibody (B01). Lane 1: PCSK7 transfected lysate (64.40 KDa). Lane 2: Non-transfected lysate.

Proprotein Convertase 7/PCSK7 Antibody - H00009159-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

Anti-PCSK7 antibody produced in mouse - SAB1406786 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PCSK7: <B>Cat. No. SAB1406786</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~65 kDa using PCSK7 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PCSK7 (216-230) antibody produced in rabbit - SAB1100709 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PCSK7 (216-230) : <B>Cat. No. SAB1100709</B>: Immunofluorescence of HUVEC cells using PCSK7 (216-230) , Cat. No. SAB1100709 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PCSK7 (141-155) antibody produced in rabbit - SAB1100708 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PCSK7 (141-155) : <B>Cat. No. SAB1100708</B>: Immunofluorescence of HUVEC cells using PCSK7 (141-155) , Cat. No. SAB1100708 (red) at a 1:200 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PCSK7 antibody produced in rabbit - HPA043181 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PCSK7: <B>Cat. No. HPA043181</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.
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