| Gene Symbol |
PCSK7
|
| Entrez Gene |
9159
|
| Alt Symbol |
LPC, PC7, PC8, SPC7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proprotein convertase subtilisin/kexin type 7
|
| Other Description |
lymphoma proprotein convertase|prohormone convertase 7|prohormone convertase PC7|proprotein convertase 7|proprotein convertase 8|proprotein convertase PC7|subtilisin/kexin-like protease PC7
|
| Swissprots |
Q96FK8 Q3C1X1 Q53GM4 B0YJ60 Q9UL57 Q16549
|
| Accessions |
AAD55137 ACA06036 EAW67303 EAW67304 EAW67305 Q16549 AB231710 BAE46876 AB231711 AB231712 AK027156 AK097207 BAG53434 AK127262 AK222907 BAD96627 AK312429 BAG35338 BC006357 AAH06357 BC010696 AAH10696 BT006870 AAP35516 DA126121 DQ890632 ABM92249 DQ893803 ABM84729 EL950661 U33849 AAB03087 U40623 AAC50417 XM_006718939 XP_006719002 XM_006718940 XP_006719003 XM_011543061 XP_011541363 XM_011543062 XP_011541364 XR_428984 XR_947870 XR_947871 NM_004716 NP_004707
|
| Function |
Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif.
|
| Subcellular Location |
Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Seems to be localized intracellularly to the trans Golgi network. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte.
|