| Gene Symbol |
ASUN
|
| Entrez Gene |
55726
|
| Alt Symbol |
C12orf11, GCT1, Mat89Bb, NET48, SPATA30
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
asunder spermatogenesis regulator
|
| Other Description |
asunder, spermatogenesis regulator homolog (Drosphila)|cell cycle regulator Mat89Bb homolog|germ cell tumor 1|protein asunder homolog|sarcoma antigen NY-SAR-95|spermatogenesis associated 30
|
| Swissprots |
B4DNK1 Q9NVM9 Q9BTX2 Q86WE2 Q9NVM5 Q9NTB6 Q96HM2
|
| Accessions |
EAW96538 EAW96539 Q9NVM9 AF274950 AAK07527 AK001222 BAA91565 AK001492 BAA91721 AK001499 BAA91725 AK225336 AK297948 BAG60263 AL137401 CAB70726 AY211927 AAO65180 BC003081 AAH03081 BC008368 AAH08368 BM684866 DB239903 XM_005253422 XP_005253479 XM_011520749 XP_011519051 XM_011520750 XP_011519052 XM_011520751 XP_011519053 XM_011520752 XP_011519054 XM_011520753 XP_011519055 XR_931311 NM_018164 NP_060634
|
| Function |
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. {ECO:0000269|PubMed:15737938, ECO:0000269|PubMed:23097494}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:23097494}.
|
| Tissue Specificity |
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis. {ECO:0000269|PubMed:12414650}.
|