CCNB1IP1

Gene Symbol	CCNB1IP1
Entrez Gene	57820
Alt Symbol	C14orf18, HEI10
Species	Human
Gene Type	protein-coding
Description	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
Other Description	E3 ubiquitin-protein ligase CCNB1IP1|human enhancer of invasion 10
Swissprots	Q9NPC3
Accessions	CAI93603 EAW66479 Q9NPC3 AA101731 AF216381 AAF36386 AI301662 AK026233 BAB15403 AK225253 AK225451 AK226037 AK309183 AL161994 CAB82326 AM393093 CAL37971 AM393651 CAL38527 BC000369 AAH00369 BC001218 AAH01218 BC004435 AAH04435 BI763317 BI771433 BI917081 BM741413 BX161423 CAD61896 BX161424 CAD61897 BX247978 CAD62312 BX334446 CB113193 DB029392 NM_182851 NM_021178 NP_067001 NM_182849 NP_878269 NM_182852 NP_878272
Function	Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL- gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis. {ECO:0000250}.
Subcellular Location	Nucleus. Chromosome. Note=Associates to the synaptonemal complex.
Tissue Specificity	Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung. {ECO:0000269|PubMed:12612082}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CCNB1IP1 full length protein - ab163657 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CCNB1IP1 protein fragment - ab163658 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

CCNB1IP1 Antibody Blocking Peptide - LS-E21375 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CCNB1IP1 Antibody Blocking Peptide - LS-E10108 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CCNB1IP1 Protein - H00057820-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CCNB1IP1 Partial Recombinant Protein - H00057820-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CCNB1IP1-Antibody-C-term-Blocking-Peptide - BP9400b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CCNB1IP1 - H00057820-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CCNB1IP1 - H00057820-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CCNB1IP1 - H00057820-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CCNB1IP1 - H00057820-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human E3 ubiquitin-protein ligase CCNB1IP1(CCNB1IP1) - CSB-YP878840HU CSB-EP878840HU CSB-BP878840HU CSB-MP878840HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CCNB1IP1 (full length, N-term HIS tag, transcript variant 1) - TP760517 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

CCNB1IP1 Blocking Peptide - abx061295 from Abbexa Category Peptide Species Human

CCNB1IP1 Peptide, Human - M34GP02642H from Creative Peptides Category Peptide Source Synthetic. Species Human

CCNB1IP1 Blocking Peptide - CBP5208 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

CCNB1IP1 peptide - orb319354 from Biorbyt Category Peptide Prices $247.00, $510.00 Sizes 1 mg, 5 mg

E3 ubiquitin-protein ligase CCNB1IP1 (CCNB1IP1), Recombinant Protein - MBS1458147 from MyBioSource Category Protein Prices $1,030.00, $1,030.00, $1,260.00, $1,260.00, $1,595.00, $1,595.00, $2,060.00, $2,060.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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