FAM120A

Gene Symbol FAM120A
Entrez Gene 23196
Alt Symbol C9orf10, DNAPTP1, DNAPTP5, OSSA
Species Human
Gene Type protein-coding
Description family with sequence similarity 120A
Other Description DNA polymerase-transactivated protein 1|DNA polymerase-transactivated protein 5|constitutive coactivator of PPAR-gamma-like protein 1|oxidative stess-associated Src activator|oxidative stress-associated Src activator
Swissprots Q4VXF4 A6NGU0 O60649 Q14688 Q86V69 Q9NZB2 Q9NZB1 Q4VXF5 Q4VXG2 Q96I21 C4AMC6
Accessions EAW62863 EAW62864 EAW62865 EAW62866 Q9NZB2 AF055017 AAC09364 AF214737 AAF72866 AF214738 AAF72867 AK091785 AK096349 AW949787 AY266457 AAP31031 AY450389 AAR21082 AY450393 AAR21086 BC007879 AAH07879 BC034935 BC075701 BC098584 AAH98584 BC111736 AAI11737 BQ020345 BQ421167 BX326996 CA310462 CA419293 CB989774 CD110412 CF135376 D80005 BAA11500 R40697 XM_005251842 XP_005251899 XM_011518412 XP_011516714 XM_011518413 XP_011516715 XM_011518414 XP_011516716 XM_011518415 XP_011516717 XM_011518416 XP_011516718 NM_001286722 NP_001273651 NM_001286723 NP_001273652 NM_001286724 NP_001273653 NM_014612 NP_055427
Function May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous- type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. {ECO:0000250, ECO:0000269|PubMed:19015244}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19015244}. Cell membrane {ECO:0000269|PubMed:19015244}; Peripheral membrane protein {ECO:0000269|PubMed:19015244}; Cytoplasmic side {ECO:0000269|PubMed:19015244}. Note=Translocates to plasma membrane upon ultraviolet exposure.
Tissue Specificity Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level). {ECO:0000269|PubMed:14585507, ECO:0000269|PubMed:19015244}.

FAM120A CRISPR/Cas9 KO Plasmid (h) - sc-411691 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM120A HDR Plasmid (h) - sc-411691-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM120A Double Nickase Plasmid (h) - sc-411691-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM120A Double Nickase Plasmid (h2) - sc-411691-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM120A CRISPR Activation Plasmid (h) - sc-411691-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM120A CRISPR Activation Plasmid (h2) - sc-411691-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM120A Lentiviral Activation Particles (h) - sc-411691-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM120A Lentiviral Activation Particles (h2) - sc-411691-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FAM120A siRNA (h) - sc-92686 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAM120A shRNA Plasmid (h) - sc-92686-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FAM120A shRNA (h) Lentiviral Particles - sc-92686-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU094621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8142 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8142 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FAM120A siRNA (Human) - CRH8076 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FAM120A - MBS8227022 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FAM120A (NM_014612.3) - SHH289289 from Creative biogene

Category siRNA
Species Reactivities Human

Human FAM120A siRNA - orb268578 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FAM120A shRNA Plasmid (Human) - CHH8076 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FAM120A miRNA 3'UTR clone - MiUTR1H-03403 from Creative biogene

Species Reactivities Human
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