Gene Symbol | ASB10 |
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Entrez Gene | 136371 |
Alt Symbol | GLC1F |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat and SOCS box containing 10 |
Other Description | ankyrin repeat and SOCS box protein 10 |
Swissprots | Q6ZUL6 A0AVH0 Q8WXI3 |
Accessions | EAL24504 EAW54020 EAW54021 EAW54022 Q8WXI3 AF417920 AAL59159 AK055536 AK125565 BAC86204 AK315114 BC126351 AAI26352 DA898875 XM_005249949 XP_005250006 NM_001142459 NP_001135931 NM_001142460 NP_001135932 NM_080871 NP_543147 |
Function | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:22156576}. Nucleus {ECO:0000269|PubMed:22156576}. Note=In the ciliary body, it is detected in the cytoplasm and perinuclear region of the pigmented ciliary epithelial layer. In the retina, it is detected in the nuclei of retinal ganglion cells. |
Tissue Specificity | Expressed in the eye. The highest expression is observed in the iris, with moderate levels in the trabecular meshwork (TM), the lamina, and the optic nerve; slightly lower levels in the ciliary body, retina, and choroid; and very low levels in the lens. {ECO:0000269|PubMed:22156576}. |
ASB-10 (D-14) - sc-104084 from Santa Cruz Biotechnology
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ASB-10 (E-15) - sc-104085 from Santa Cruz Biotechnology
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ASB-10 (H-63) - sc-382825 from Santa Cruz Biotechnology
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ASB-10 (QQ6) - sc-100677 from Santa Cruz Biotechnology
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Anti-ASB10 antibody - ab200357 from Abcam
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Anti-ASB10 antibody - ab58133 from Abcam
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Anti-ASB10 antibody - N-terminal - ab173343 from Abcam
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Anti-ASB10 Antibody (aa76-103, AP) - LS-C251832 from LifeSpan Bioscience
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Anti-ASB10 Antibody (aa76-103, APC) - LS-C251833 from LifeSpan Bioscience
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Anti-ASB10 Antibody (aa76-103, Biotin) - LS-C251834 from LifeSpan Bioscience
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Anti-ASB10 Antibody (aa76-103, FITC) - LS-C251835 from LifeSpan Bioscience
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Anti-ASB10 Antibody (aa76-103, Azide-free, HRP) - LS-C251836 from LifeSpan Bioscience
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Anti-ASB10 Antibody (aa76-103, PE) - LS-C251837 from LifeSpan Bioscience
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Anti-ASB10 Antibody (aa48-153) - LS-C306391 from LifeSpan Bioscience
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Anti-ASB10 Antibody (aa76-103) - LS-C159130 from LifeSpan Bioscience
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Anti-ASB10 Antibody (aa75-103) - LS-C319624 from LifeSpan Bioscience
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ASB10 Antibody - NBP1-86145 from Novus Biologicals
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ASB10 Antibody (1F3) - H00136371-M02 from Novus Biologicals
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ASB10 Antibody - H00136371-A01 from Novus Biologicals
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ASB10 Polyclonal Antibody - bs-4653R from Bioss
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Anti-ASB10 antibody produced in rabbit - HPA004178 from Sigma-Aldrich
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Monoclonal Anti-ASB10 antibody produced in mouse - WH0136371M2 from Sigma-Aldrich
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ASB10-Antibody-N-term - AP17629a from Abgent, a WuXi AppTec company
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ASB10-Antibody-monoclonal-M02 - AT1209a from Abgent, a WuXi AppTec company
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ASB10 Antibody - N-terminal region (OAAB13060) - OAAB13060 from Aviva Systems Biology
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